国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (2): 150-152.doi: 10.3760/cma.j.issn.1673-422X.2015.02.019

• 综述 • 上一篇    下一篇

肥胖与卵巢癌的相关性

李霞辉,张学梅,蒋葵   

  1. 116027大连医科大学附属第二医院肿瘤内科(李霞辉、蒋葵);大连大学医学院(张学梅)
  • 出版日期:2015-02-08 发布日期:2015-02-02
  • 通讯作者: 蒋葵 E-mail:jk0411@163.com
  • 基金资助:

    国家科技支撑计划(2012BAK25B00)

Correlation between obesity and ovarian cancer

Li Xiahui, Zhang Xuemei, Jiang Kui   

  1. Department of Medical Oncology, Second Hospital of Dalian Medical University, Dalian 116027, China
  • Online:2015-02-08 Published:2015-02-02
  • Contact: Jiang Kui E-mail:jk0411@163.com

摘要: 肥胖不仅增加卵巢癌的发生危险,而且与卵巢癌的不良预后相关。其病因学机制可能与肥胖引起雌激素、胰岛素及胰岛素样生长因子水平升高,以及多种脂肪细胞因子等因素共同作用相关,影响卵巢癌的治疗效果和预后。因此,保持合适的体重可以预防和控制卵巢癌的发生和发展。

关键词: 肥胖症, 卵巢肿瘤, 人体质量指数

Abstract: Obesity increases the risk of ovarian cancer, and it is associated with the poor prognosis of ovarian cancer. Its pathogenic mechanism may be associated with the increased level of serum estrogen, insulin and insulinlike growth factors1 induced by obesity and a variety of adipocytokines, which has an impact on the therapeutic result and prognosis of ovarian cancer. Maintaining a proper weight may prevent the development of ovarian cancer.

Key words: Obesity, Ovarian neoplasms, Body mass index