乳腺癌BRCA1、BRCA2基因突变及其临床应用

doi:10.3760/cma.j.issn.1673-422X.2015.02.015

摘要/Abstract

摘要： 乳腺癌的发生与遗传因素密切相关。研究表明，乳腺癌易感基因(BRCA)1、2在乳腺癌的发生、发展过程中具有重要作用，针对BRCA基因突变的研究对乳腺癌的预防、诊断及治疗具有重要意义。

关键词: 乳腺肿瘤, 基因, BRCA1, 基因, BRCA2, 突变, 临床应用

Abstract: The occurrence of breast cancer is closely related to genetic factors. BRCA1 and BRCA2, breast cancer susceptibility genes, play important roles in the occurrence and development of breast cancer. The researches on germline mutations in BRCA1 and BRCA2 are of great significance in prevention, diagnosis and treatment of breast cancer.

Key words: Breast neoplasms, Genes, BRCA1, Genes, BRCA2, Mutation, Clinical application

栗辰,黄焰. 乳腺癌BRCA1、BRCA2基因突变及其临床应用[J]. 国际肿瘤学杂志, 2015, 42(2): 138-140.

Li Chen, Huang Yan. Advances of BRCA1, BRCA2 mutation and their clinical applications[J]. Journal of International Oncology, 2015, 42(2): 138-140.

参考文献

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