炎症对上皮间质转化的调控机制

doi:10.3760/cma.j.issn.1673-422X.2014.02.004

国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (2): 90-93.doi: 10.3760/cma.j.issn.1673-422X.2014.02.004

炎症对上皮间质转化的调控机制

单泽志, 严雪冰, 金志明

200233 上海交通大学附属第六人民医院普外科

收稿日期:2013-09-29 修回日期:2013-12-08 出版日期:2014-02-08 发布日期:2014-01-26
通讯作者: 金志明，E-mail: jzmgyp@aliyun.com E-mail:jzmgyp@aliyun.com

Regulatory mechanisms of inflammation in epithelial mesenchymal transition

Shan Zezhi, Yan Xuebing, Jin Zhiming

Department of General Surgery, Sixth People′s Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China

Received:2013-09-29 Revised:2013-12-08 Online:2014-02-08 Published:2014-01-26
Contact: Jin Zhiming E-mail:jzmgyp@aliyun.com

摘要/Abstract

摘要： 炎症在肿瘤发生发展中发挥重要作用。上皮间质转化（EMT)是肿瘤增殖、侵袭及转移过程中的重要分子机制。越来越多的研究表明，炎症与EMT密切相关。在炎症微环境中，细胞因子和炎症微生物都参与EMT的调控。

关键词: 炎症, 肿瘤侵润, 肿瘤转移, 上皮间质转化

Abstract: Inflammation plays an important role in the initiation and development of tumor. Epithelialmesenchymal transition (EMT) acts as a critical molecular mechanism involved in the proliferation, invasion and metastasis of tumor. Mounting studies show that inflammation is related with EMT closely. In the inflammatory microenvironment, both cytokines and microbes take part in the regulation of EMT.

Key words: Inflammation, Neoplasm invasiveness, Neoplasm metastasis, Epithelial mesenchymal transition

单泽志, 严雪冰, 金志明. 炎症对上皮间质转化的调控机制[J]. 国际肿瘤学杂志, 2014, 41(2): 90-93.

Shan Zezhi, Yan Xuebing, Jin Zhiming. Regulatory mechanisms of inflammation in epithelial mesenchymal transition[J]. Journal of International Oncology, 2014, 41(2): 90-93.

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炎症对上皮间质转化的调控机制

Regulatory mechanisms of inflammation in epithelial mesenchymal transition

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