肺癌免疫治疗相关心肌炎的研究进展

doi:10.3760/cma.j.cn371439-20251106-00051

摘要/Abstract

摘要：

免疫检查点抑制剂治疗是肺癌的重要治疗方式，但其可导致与免疫相关的不良事件，包括潜在严重的心脏毒性如心肌炎，导致治疗延迟或中断。严重的心脏毒性事件甚至可能导致患者死亡。提高对免疫检查点抑制剂相关心肌炎的关注，并在临床应用中针对高危患者采取适当预防和干预措施，可最大限度地降低心肌炎发生风险和危害程度。

关键词: 肺肿瘤, 免疫检查点抑制剂, 心肌炎

Abstract:

Immune checkpoint inhibitor treatment is an important treatment option for lung cancer. However， it can cause immune-related adverse events， including potentially severe cardiac toxicity， such as myocarditis， which can lead to treatment delays or discontinuation. Severe cardiac toxicity events can even result in patient death. Increasing attention to immune checkpoint inhibitor-associated myocarditis and implementing appropriate preventive and intervention measures for high-risk patients in clinical applications can minimize the risk and severity of myocarditis.

Key words: Lung neoplasms, Immune checkpoint inhibitors, Myocarditis

赵娟, 余娇凤, 魏澳娇, 戴以雪, 赵艳, 符叶, 赵明利. 肺癌免疫治疗相关心肌炎的研究进展[J]. 国际肿瘤学杂志, 2026, 53(5): 311-316.

Zhao Juan, Yu Jiaofeng, Wei Aojiao, Dai Yixue, Zhao Yan, Fu Ye, Zhao Mingli. Research progress on myocarditis associated with immunotherapy in lung cancer[J]. Journal of International Oncology, 2026, 53(5): 311-316.

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