Journal of International Oncology ›› 2015, Vol. 42 ›› Issue (8): 693-.doi: 10.3760/cma.j.issn.1673422X.2015.09.014

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Circulating microRNA in lung cancer

QU  Li-Li, LIU  Xiao-Qing   

  1. Department of Lung Cancer, Affiliated Hospital of Academy of Military Medical Science
  • Online:2015-09-08 Published:2015-08-12

Abstract: MicroRNAs (miRNAs) negatively mediate the post transcriptional target genes by degrading mRNAs and inhibiting translation of protein. Deregulation of miRNAs are directly or indirectly correlated with tumorigenesis and development of cancer. Currently, the application of miRNAs as a noninvasive potential biomarker with high stability is under investigation.