Abstract: Scutellarin (SC), a botanical extract, possesses a variety of suppressing free radical generation, antiinflammatory, cardioprotection and antivirus activity. Recently, many studies show that SC has inhibitory effects on the growth of many tumors and is a kind of potential antitumor drug. Its antitumor mechanisms mainly include inducing apoptosis, arresting cell cycle, enhancing the adhesion between cells, inhibiting tumor invasion, reversing multidrug resistance, anti-angiogenesis and so on.