Abstract: ObjectiveTo evaluate the clinical effect of CT guided localization with a hookwire system united with single port videoassisted thoracoscopic resection (VATS) for small ground glass opacity (GGO) pulmonary nodules (CT lesion diameter<1.5 cm and no pleural changes). MethodsFifteen patients with small GGO pulmonary nodules who underwent CTguided transthoracic localization with a hookwire system in operation room after anesthesia were performed with single port VATS from August 2009 to March 2013. The accuracy of puncture location, complications, resection rate and pathological results were evaluated. ResultsAll patients underwent CTguided hookwire localization and single port VATS resection. The success rate of localization was 100%, and the average procedure time was (13.60±2.06)min, only 1 patient occurred minimal pneumothorax. The resection rate of single port VATS was 100%, and lobectomy performed in 1 patient, segmentectomy in 1, and local resection in 13. Pathological diagnosis: adenocarcinoma in situ in 9, atypical adenomatous hyperplasia (AAH) in 5, AAH and adenocarcinoma in situ in 1. Postoperation followup showed all patients survived, and no recurrence and metastasis. ConclusionIn operation, use of CT guided localization with a hookwire system for small GGO pulmonary nodules (CT lesion diameter<1.5 cm and no pleural changes) united with videoassisted thoracoscopic resection is accurate, quick and safe, and it has good clinical value.

Key words: Coin lesion, pulmonary, Thoracoscopy, Pneumonectomy, CTguidance