Effects of microRNAs on sensitivity of chemotherapy in lung cancer

doi:10.3760/cma.j.issn.1673-422X.2014.01.014

Abstract

Abstract: Researches show that abnormal expressions of microRNAs (miRNAs) can affect chemotherapy sensitivity of lung cancer. Moreover, some miRNAs may serve as biomarkers for sensitivity and resistance of chemotherapy, such as miR125, miR497, miR21 and so on. It is found that some signaling pathways involve in the regulation of miRNAs for chemotherapy sensitivity. But a large number of regulatory mechanisms are not yet clear, and need to be further explored.

Key words: MicrRNAs, Carcinoma, non-small-cell lung, Chemotherapy sensitivity

Tian Jing, Wu Hailiang. Effects of microRNAs on sensitivity of chemotherapy in lung cancer[J]. Journal of International Oncology, 2014, 41(1): 44-46.

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