Journal of International Oncology ›› 2013, Vol. 40 ›› Issue (10): 736-738.

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Carcinogenesis of cell cycle-related kinase

XIE  Xu, TIAN  Ye, TAN  Guang   

  1. Department of Hepatobiliary Surgery, First Affiliated Hospital of Dalian Medical University, Dalian 116011, china
  • Online:2013-10-08 Published:2013-09-23
  • Contact: TAN Guang, E-mail: tanguang009@sina.com E-mail:tanguang009@sina.com

Abstract: Cell cycle-related kinase (CCRK) as a novel CDK-activating kinase plays a significant role in cell cycle regulation. Related studies confirm that CCRK is overexpressed in various tumors, and is associated with poor prog­nosis of the patients, which indicates that CCRK takes part in the generation and development of the tumor.

Key words: Gene expression regulation, neoplastic, Cyclin-dependent kinases, Cell cycle