Journal of International Oncology ›› 2012, Vol. 39 ›› Issue (12): 889-892.

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Hypoxia inducible factor-1 and tumor

WANG  Rui, LIAO  Sheng-Tao, LIU  Yun-Lai   

  1. Company 7 of Student Brigade, Third Military Medical University, Chongqing 400038, China
  • Online:2012-12-08 Published:2012-11-15
  • Contact: Corresponding author: LIU Yun-lai, E-mail: fooljohn2010@hotmail.com E-mail:fooljohn2010@hotmail.com

Abstract: Hypoxia inducible factor-1(HIF-1) is usually highly expressed in tumor cells, and can promote tumor growth. HIF-1 is correlated with tumor condition, the diagnosis and the prognosis. Therefore, HIF-1 can be used for tumor treatment in the level of transcriprion, pro-transcriprion and target. It is possible to improve the treatment efficiency, and to lengthen patients lifespan.

Key words: Neoplasms, Hypoxia-inducible factor 1, Diagnosis, Therapy