Journal of International Oncology ›› 2019, Vol. 46 ›› Issue (6): 346-349.doi: 10.3760/cma.j.issn.1673-422X.2019.06.006

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Expression and mechanisms of long non-coding RNAs SNHG15 in cancers

Li Yingying, Huang Junxing   

  1. Department of Oncology, Taizhou People′s Hospital Affiliated to Medical College of Nantong University, Taizhou 225300, China
  • Online:2019-06-08 Published:2019-07-11
  • Contact: Huang Junxing, Email: hjxtz@163.com E-mail: hjxtz@163.com
  • Supported by:

    Medical Innovation Team Project of Jiangsu Province of China (CXTDA2017042)

Abstract: As a kind of long non-coding RNAs (lncRNAs), small nucleolar RNA host gene 15 (SNHG15) is located on chromosome 7. In recent years, studies have shown that lncRNA SNHG15 is over expressed in various types of cancers such as glioma, thyroid cancer, breast cancer, lung cancer, gastric cancer, colorectal cancer, liver cancer, renal carcinoma, pancreatic cancer, osteosarcoma, and it can promote the proliferation, invasion, metastasis of malignant tumors and lead to poor prognosis of tumor patients through different signal pathways.

Key words: RNA, long noncoding, Neoplasms, Small nucleolar RNA host gene 15