Comparison of magnifying endoscopy combined with narrowband imaging and endoscopic ultrasonography for assessment of the invasion depth of early esophageal cancer

doi:10.3760/cma.j.issn.1673-422X.2019.01.005

Abstract

Abstract: Objective To investigate the clinical utility of magnifying endoscopy combined with narrowband imaging (ME-NBI) and endoscopic ultrasonography (EUS) in predicting the depth of early esophageal cancer. Methods Sixtyeight patients with early esophageal cancer after gastroscopic and pathological diagnosis were enrolled in Jiangsu Provincal Hospital of Traditional Chinese Medicine from January 2017 to May 2018, ME-NBI and EUS were performed preoperatively to determine the depth of lesion infiltration respectively, the accuracies of the two methods were calculated by referring to the postoperative pathology, and the McNemar test and Kappa test were used for comparison. Results The lesion confined to shallow mucosa and submucosa superficial layer was confirmed in 57 patients by postoperative pathology, submucosa superficial below in 11 patients. Compared with that of histology, the ability of assessment of the invasion depth was moderately consistent with MENBI (McNemar test P=0.508; Kappa=0.560, P＜0.001), not with EUS (McNemar test P=0.019; Kappa=0.266, P=0.015). The accuracy for assessing invasion depth of early esophageal cancer was 86.8% (59/68) by MENBI, 72.1% (49/68) by EUS, respectively, with statistically significant difference (McNemar test P=0.015; Kappa=0.258, P=0.026). Conclusion ME-NBI and EUS can help to determine the infiltration level of early esophageal cancer. The accuracy of MENBI is higher, which is of high value for the formulation of surgical plans for patients.

Key words: Esophageal neoplasms, Endosonography, Neoplasm invasiveness, Magnifying endoscopy with narrow-band imaging

Wu Dapeng, Sun Renhu, Li Yang, Han Shutang, Xiao Jun. Comparison of magnifying endoscopy combined with narrowband imaging and endoscopic ultrasonography for assessment of the invasion depth of early esophageal cancer[J]. Journal of International Oncology, 2019, 46(1): 22-26.

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