Abstract: Studies have found that thalidomide has antitumor activity due to its inhibitory effect on angiogenesis and immunomodulation, which has been effectively used in targeted therapy resistant nonsmall cell lung cancer, castrationresistant prostate cancer, colorectal cancer, advanced hepatocarcinoma and advanced gastric cancer. Many clinical studies have also found that it has certain practical value in the aspects of improvement of cancer cachexia and chemotherapyinduced nausea and vomiting.

Key words: Neoplasms, Therapeutic uses, Thalidomide