Journal of International Oncology ›› 2018, Vol. 45 ›› Issue (4): 226-228.doi: 10.3760/cma.j.issn.1673-422X.2018.04.009

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Relationship between microRNA-335 expression and prognosis in tumor tissue

Xu Xiaoyan, Wu Yinjie, Yin Ling, Xu Fei, Yu Zhuang   

  1. Department of Tumor Chemotherapy, Affiliated Hospital of Qingdao University, Qingdao 266000, China
  • Online:2018-04-08 Published:2018-05-16
  • Contact: Yu Zhuang, Email: yuzhuang2002@163.com E-mail:yuzhuang2002@163.com
  • Supported by:

    Natural Science Foundation of Shandong Province of China (ZR2017MH062)

Abstract: The low expression of microRNA-335 (miR-335) indicates poor prognosis in many types of cancer, such as gastric cancer, breast cancer, lung cancer and other solid tumors. The low expression of miR-335 can promote tumor metastasis and progression, and is associated with histological grading, lymph node metastasis and tumor staging, which  provids a new way of thinking for the diagnosis and treatment of tumors.

Key words: MicroRNAs, Neoplasms, Prognosis