Adverse reactions and treatment measures of advanced solid tumors treated with antibody-drug conjugates

doi:10.3760/cma.j.cn371439-20220208-00039

Abstract

Abstract:

Novel antibody-drug conjugates （ADCs） are a hot spot in the research and development of new drugs for advanced solid tumors. ADCs have achieved significant efficacy in the treatment of advanced breast cancer, urothelial carcinoma, gastric cancer and other solid tumors, but their adverse reactions such as ocular toxicity, pulmonary toxicity, hematological toxicity, and liver toxicity cannot be ignored, and it is crucial to effectively deal with the adverse reactions of ADCs.

Key words: Antibody-drug conjugate, Adverse reactions, Occurrence mechanism, Treatment measures

Pang Jingdan, Du Yingying, Da Jie. Adverse reactions and treatment measures of advanced solid tumors treated with antibody-drug conjugates[J]. Journal of International Oncology, 2022, 49(4): 220-224.

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