Abstract: Adiponectin is a kind of adipocytespecific protein which is only inversely related with obesity by now. It is involved in enhancing insulin sensitivity, antiatherogenic and antiinflammatory activities. Recent studies have reported that adiponectin is closely correlated with the genesis and development of a variety of obesity related malignant tumors, especially postmenopausal breast cancer. Obesity is an independent risk factor for the development of breast cancer. Recently researches about the correlation between adiponectin and breast cancer relations and the action mechanisms, signaling pathways have made a progress.

Key words: Adiponectin, Receptors,adiponectin, Breast neoplasms, Signal transduction