HIV/AIDS相关淋巴瘤研究进展

doi:10.3760/cma.j.issn.1673-422X.2015.06.021

摘要/Abstract

摘要： 人类免疫缺陷病毒（HIV）/获得性免疫缺陷综合征（AIDS）相关淋巴瘤（ARL）是一组异质性肿瘤，预后较差。近年来阐明的发病机制包括HIV引起的免疫损伤、EB病毒的感染及基因的改变。ARL的病理类型主要有4种，即弥漫大B细胞淋巴瘤、Burkitt淋巴瘤、原发渗出性淋巴瘤和浆母细胞淋巴瘤。形态学特征、免疫标记和遗传学特点的联合应用有助于诊断和鉴别诊断，从而有利于及时治疗和改善预后。

关键词: HIV感染, 淋巴瘤, 肿瘤形成过程, 病理学

Abstract: HIV/AIDS related lymphoma (ARL) are a group of heterogeneity of neoplasms, and they have poor prognosis. The factors of pathogenesis elucidated in recent years include immune injury caused by HIV, EB virus infection and genetic changes. There are four pathological types of ARL, including diffuse large B cell lymphoma, Burkitt lymphoma, plasmablastic lymphoma and primary effusion lymphoma. Morphological characteristics, immunophenotype markers and clinical data should be combined to make diagnosis and differential diagnosis, which will facilitate timely treatment and improve prognosis.

Key words: HIV infections, Lymphoma, Neoplastic processes, Pathology

王迪,冯艳玲. HIV/AIDS相关淋巴瘤研究进展[J]. 国际肿瘤学杂志, 2015, 42(6): 475-477.

Wang Di, Feng Yanling. Research progress of HIV/AIDS related lymphoma[J]. Journal of International Oncology, 2015, 42(6): 475-477.

参考文献

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