循环肿瘤细胞检测的临床应用

doi:10.3760/cma.j.issn.1673-422X.2014.02.007

国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (2): 99-102.doi: 10.3760/cma.j.issn.1673-422X.2014.02.007

循环肿瘤细胞检测的临床应用

李庞, 高杰, 李胜

250062 济南大学山东省医学科学院医学与生命科学学院（李庞）；山东省烟台市毓璜顶医院肝胆外科（高杰）；山东省医学科学院科技开发处（李胜）

收稿日期:2013-09-05 修回日期:2013-12-04 出版日期:2014-02-08 发布日期:2014-01-26
通讯作者: 李胜，E-mail: drlisheng@sohu.com E-mail:drlisheng@sohu.com
基金资助:
国家重点基础研究发展计划（973计划）项目（2011CB504302）

Clinical application of circulating tumor cells detection

Li Pang, Gao Jie, Li Sheng

College of Medical and Life Sciences, Shandong Academy of Medical Sciences, Ji′nan University, Ji′nan 250062, China

Received:2013-09-05 Revised:2013-12-04 Online:2014-02-08 Published:2014-01-26
Contact: Li Sheng E-mail:drlisheng@sohu.com

摘要/Abstract

摘要： 循环肿瘤细胞（CTC）计数在判断肿瘤的临床分期、评估肿瘤预后、进行疗效监测中的应用价值已获得广泛认可，但还需要大量研究来建立标准化评价体系并进行临床试验验证。CTC的分子生物学检测不仅可以对CTC计数进行完善，更因为其在肿瘤的辅助诊断和指导个体化治疗中的巨大潜力以及对于了解肿瘤转移的生物学行为的重大意义将成为未来的研究热点。

关键词: 循环肿瘤细胞, 肿瘤分期, 诊断, 预后, 治疗结果

Abstract: irculating tumor cell (CTC) count is widely recognized in determining tumor stage, assessing prognosis, monitoring therapy response. But a lot of researches and clinical experiments are needed to establish a standardized evaluation system. Molecular detection of CTC not only can improve the CTC count, but also have immense potential for the auxiliary diagnosis and individual treatment of tumors and significance for understanding the biological behavior of tumor metastasis. It will become the hot spot of future research.

Key words: Circulating neoplasm cells, Neoplasm staging, Diagnosis, Prognosis, Treatment outcome

李庞, 高杰, 李胜. 循环肿瘤细胞检测的临床应用[J]. 国际肿瘤学杂志, 2014, 41(2): 99-102.

Li Pang, Gao Jie, Li Sheng. Clinical application of circulating tumor cells detection[J]. Journal of International Oncology, 2014, 41(2): 99-102.

参考文献

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循环肿瘤细胞检测的临床应用

Clinical application of circulating tumor cells detection

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