国际肿瘤学杂志

国际肿瘤学杂志 ›› 2012, Vol. 39 ›› Issue (7): 533-537.

• 综述 • 上一篇    下一篇

胃癌化疗相关基因的研究进展

覃勇,郭红   

  1. 重庆市第三军医大学第二附属新桥医院消化内科
  • 出版日期:2012-08-06 发布日期:2012-08-06
  • 通讯作者: 郭红，E-mail: haojia2004@yahoo.com.cn E-mail:haojia2004@yahoo.com.cn

Gastric cancer chemotherapy related genes

QIN  Yong, GUO  Hong   

  1. Department of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China
  • Online:2012-08-06 Published:2012-08-06
  • Contact: GUO Hong, E-mail: haojia2004@yahoo.com.cn E-mail:haojia2004@yahoo.com.cn

PDF

1896

被引次数

3

摘要： 基因的表达对胃癌的药物治疗有着十分重要的影响，有的基因与药物的疗效相关，有的基因与药物的不良反应相关，而有的基因则与肿瘤对药物的敏感性相关。胃癌化疗相关基因的研究对提高患者化疗疗效有着重要的指导作用。近年来对胃癌化疗相关基因的研究取得了较大进展，特别是在铂类、嘧啶类、紫杉醇类以及靶向药物相关基因的研究。

关键词: 胃肿瘤, 药物疗法, 基因表达

Abstract: The expression of genes have an important effect to gastric cancer chemotherapy. Some genes are related the therapeutic efficacy of drugs, some genes are related the untoward effects of drug, and some genes are related the sensitivity of the tumor to drug. Chemotherapy related genes may play an important guiding role to improve the curative effect of chemotherapy patients. In recent years, the gastric cancer chemotherapy related genes have made great progress, especially in platinum, fluorouracil, paclitaxel and targeted medicine related genes.

Key words: Stomach neoplasms, Drug therapy, Gene expression