SPRY4-IT1与乳腺癌

doi:10.3760/cma.j.cn371439-20230616-00119

摘要/Abstract

摘要：

长非编码RNA（lncRNA）是一种不编码表达蛋白质的RNA分子，在多种肿瘤的发生、发展中发挥着重要作用。SPRY4-IT1作为一种lncRNA，在乳腺癌组织中高表达，可作为乳腺癌上下游调控因子，促进乳腺癌的进展并与乳腺癌分期及预后密切相关。深入研究SPRY4-IT1与乳腺癌的相关分子机制，可为发现乳腺癌早期诊断生物标志物、评估疾病预后和寻找靶向位点提供新的思路。

关键词: RNA，长链非编码, 乳腺肿瘤, SPRY4-IT1

Abstract:

Long non-coding RNA （lncRNA） is an RNA molecule that does not code to express proteins， and plays an important role in the occurrence and development of a variety of tumors. As an lncRNA， SPRY4-IT1 is highly expressed in breast cancer tissues， and can be used as an upstream and downstream regulator of breast cancer， promoting the progression of breast cancer， and is closely related to breast cancer stage and prognosis. In-depth study of the molecular mechanism associated with SPRY4-IT1 and breast cancer can provide new ideas for discovering biomarkers for early diagnosis of breast cancer， assessing disease prognosis and finding targeting sites.

Key words: RNA， long noncoding, Breast neoplasms, SPRY4-IT1

闫学敏, 武霄勇, 张佳谊, 文锦旭, 王跃欣. SPRY4-IT1与乳腺癌[J]. 国际肿瘤学杂志, 2023, 50(10): 627-630.

Yan Xuemin, Wu Xiaoyong, Zhang Jiayi, Wen Jinxu, Wang Yuexin. SPRY4-IT1 and breast cancer[J]. Journal of International Oncology, 2023, 50(10): 627-630.

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