国际肿瘤学杂志 ›› 2023, Vol. 50 ›› Issue (6): 362-367.doi: 10.3760/cma.j.cn371439-20230404-00072

• 综述 • 上一篇    下一篇

放疗联合系统治疗在乳腺癌中的应用进展

李青珊1, 谢鑫2, 张楠3(), 刘帅3()   

  1. 1潍坊医学院临床医学院,潍坊 261041
    2山东第一医科大学研究生部,济南 250117
    3山东第一医科大学附属中心医院乳腺疾病诊疗中心,济南 250013
  • 收稿日期:2023-04-04 修回日期:2023-04-23 出版日期:2023-06-08 发布日期:2023-07-11
  • 通讯作者: 张楠,Email:zlkzn2016@126.com;刘帅,Email:discoveryliu@163.com
    李青珊和谢鑫对本文有同等贡献
  • 基金资助:
    山东省自然科学基金(ZR2020QH252);山东省医学会临床科研资金—齐鲁专项(YXH2022ZX02168);济南市卫生健康委员会大数据科技计划(2022-YBD-03);济南市卫生健康委员会科技计划(2020-4-24);济南市临床医学科技创新计划(202019005)

Research progress on the application of combining radiotherapy and systemic therapy in breast cancer

Li Qingshan1, Xie Xin2, Zhang Nan3(), Liu Shuai3()   

  1. 1School of Clinical Medicine,Weifang Medical University,Weifang 261041,China
    2School of Graduate,Shandong First Medical University,Jinan 250117,China
    3Breast Center,Central Hospital Affiliated to Shandong First Medical University,Jinan 250013,China
  • Received:2023-04-04 Revised:2023-04-23 Online:2023-06-08 Published:2023-07-11
  • Contact: Zhang Nan,Email:zlkzn2016@126.com;Liu Shuai,Email:discoveryliu@163.com
    Li Qingshan and Xie Xin are contributed equally to the article
  • Supported by:
    Natural Science Foundation of Shandong Province of China(ZR2020QH252);Clinical Research Foundation of Shandong Medical Association—Qilu Special Project(YXH2022ZX02168);Big Data Technology Plan of Jinan Municipal Health Commission(2022-YBD-03);Science and Technology Plan of Jinan Municipal Health Commission(2020-4-24);Clinical Medical Science Innovation Plan of Jinan Municipal(202019005)

摘要:

放疗联合化疗、内分泌治疗、分子靶向治疗、免疫治疗相较于单一治疗不仅可缩短治疗周期,也可提高局部控制率,延长患者生存期,而联合治疗的安全性仍需进一步明确,以综合评估其可行性。探索放疗联合系统治疗的疗效及安全性将为临床获益患者提供依据。

关键词: 乳腺肿瘤, 放射疗法, 药物疗法, 联合, 分子靶向治疗, 免疫疗法

Abstract:

Compared with single therapy,radiotherapy combined with chemotherapy,endocrine therapy,molecular targeted therapy and immunological therapy can not only shorten the treatment cycle,but also improve the local control rate and prolong the survival of patients. However,the safety of combined therapy still needs to be further clarified to comprehensively evaluate the feasibility. Therefore,exploring the efficacy and safety of radiotherapy combined with systematic therapy will provide evidence for clinical benefits.

Key words: Breast neoplasms, Radiotherapy, Drug therapy, combination, Molecular targeted therapy, Immunotherapy