国际肿瘤学杂志 ›› 2021, Vol. 48 ›› Issue (1): 61-64.doi: 10.3760/cma.j.cn371439-20200527-00012

• 综述 • 上一篇    

常见的宫颈癌主动靶向纳米药物传输系统

丁绪超1, 曹莉莉1,2()   

  1. 1山东第一医科大学第一附属医院(山东省千佛山医院)肿瘤科,济南 250014
    2山东省风湿免疫病转化医学重点实验室,济南 250014
  • 收稿日期:2020-05-27 修回日期:2020-08-29 出版日期:2021-01-08 发布日期:2021-01-21
  • 通讯作者: 曹莉莉 E-mail:cll@sdu.edu.cn
  • 基金资助:
    山东省重点研发计划(2019GSF108180);济南市科技发展计划(201907119);山东省中医药科技发展计划(2019-0378);山东第一医科大学第一附属医院培育基金(QYPY2019NSFC1015)

Common active targeting nano drug delivery systems for cervical cancer

Ding Xuchao1, Cao Lili1,2()   

  1. 1Department of Oncology, First Affiliated Hospital of Shandong First Medical University (Shandong Qianfoshan Hospital), Jinan 250014, China
    2Shandong Key Laboratory of Translational Medicine of Rheumatic and Immune Disease, Jinan 250014, China
  • Received:2020-05-27 Revised:2020-08-29 Online:2021-01-08 Published:2021-01-21
  • Contact: Cao Lili E-mail:cll@sdu.edu.cn
  • Supported by:
    Shandong Key Research and Development Plan(2019GSF108180);Jinan Science and Technology Development Plan(201907119);Shandong Province Traditional Chinese Medicine Technology Development Plan(2019-0378);First Affiliated Hospital Cultivation Fund of Shandong First Medical University(QYPY2019NSFC1015)

摘要:

宫颈癌主动靶向纳米药物传输系统通过特定的配体-受体相互作用将载药纳米颗粒定向地运送到肿瘤细胞,具有减少药物不良反应、增强药物疗效等优点。了解常见的宫颈癌主动靶向纳米药物传输系统对探索新的载体、药物和作用靶点具有重要意义。

关键词: 宫颈肿瘤, 纳米粒子, 分子靶向治疗

Abstract:

Cervical cancer active targeting nano drug delivery system delivers drug-loaded nanoparticles to cancer cells in a targeted way through specific ligand-receptor interaction, which has the advantages of reducing adverse drug reactions and improving drug efficacy. It is of great significance to understand the active targeting nano drug delivery system for cervical cancer to explore new carriers, drugs and targets.

Key words: Uterine cervical neoplasms, Nanoparticles, Molecular targeting treatment