国际肿瘤学杂志

国际肿瘤学杂志 ›› 2018, Vol. 45 ›› Issue (5): 312-314.doi: 10.3760/cma.j.issn.1673422X.2018.05.014

• 综述 • 上一篇    下一篇

滤泡辅助性T细胞与淋巴瘤的相关性

杨清波,刘凡,于建渤   

  1. 157011 牡丹江医学院附属红旗医院病理诊断中心
  • 出版日期:2018-05-08 发布日期:2018-05-23
  • 通讯作者: 于建渤,Email: jianboyu2001@vip.sina.com E-mail:jianboyu2001@vip.sina.com
  • 基金资助:

     黑龙江省博士后科研启动基金（LBHQ16224）

Relationship between follicular helper T cells and lymphoma

Yang Qingbo, Liu Fan, Yu Jianbo   

  1. Department of Pathology, Affiliated Hongqi Hospital of Mudanjiang Medical College, Mudanjiang 157011, China
  • Online:2018-05-08 Published:2018-05-23
  • Contact: Yu Jianbo E-mail:jianboyu2001@vip.sina.com
  • Supported by:

    Postdoctoral Scientific Research Developmental Foundation of Heilongjiang Province of China (LBHQ16224)

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摘要： 滤泡辅助性T细胞（TFh）是近期研究发现的一类新型CD4+辅助性T细胞亚群，研究表明其与自身免疫性疾病、免疫缺陷等疾病以及淋巴瘤患者不良预后密切相关。同时，TFh细胞与部分非特指型T细胞淋巴瘤存在密切关系。但是，TFh细胞在肿瘤微环境中的作用有待进一步深入研究。

关键词: T淋巴细胞, 淋巴瘤

Abstract: The follicular helper T cell (TFh) is a new subset of CD4+ helper T cells discovered in recent studies. Studies have shown that it  is associated with diseases such as immune diseases, immunodeficiency and poor prognosis of patients with lymphoma. At the same time, there is a close relationship between TFh cells and some nonspecific T cell lymphomas. However, the role of TFh cells in the tumor microenvironment needs to be further studied.  

Key words: Tlymphocytes, Lymphoma