国际肿瘤学杂志

国际肿瘤学杂志 ›› 2017, Vol. 44 ›› Issue (8): 708-710.doi: 10.3760/cma.j.issn.1673422X.2017.09.017

• 综述 • 上一篇    下一篇

局限期小细胞肺癌放疗研究进展

程国威, 孙莉   

  1. 100122 北京市朝阳区桓兴肿瘤医院放疗科
  • 出版日期:2017-09-08 发布日期:2017-10-31
  • 通讯作者: 程国威，Email： dxkhy7@163.com E-mail:dxkhy7@163.com

Radiotherapy for limitedstage small cell lung cancer

Cheng Guowei, Sun Li   

  1. Department of Radiotherapy, Huanxing Tumor Hospital of Chaoyang District, Beijing 100122, China
  • Online:2017-09-08 Published:2017-10-31
  • Contact: Cheng Guowei E-mail:dxkhy7@163.com

PDF

736

被引次数

1

摘要： 小细胞肺癌（SCLC）具有恶性程度高和易远处转移等特点。约25%～30%的SCLC患者初诊时为局限期（limitedstage，LS）SCLC。LSSCLC放疗参与的时机以早期胸部放疗更具生存优势，以EP方案（依托泊苷+顺铂）化疗同时合并放疗的时序被广泛接受，以CT、MRI、PET可见的肿瘤为靶区，放疗剂量和分割方式以提高放疗总剂量或者是改变放疗分割方式为主，预防性全脑照射可提高3年生存率、降低脑转移率。

关键词: 癌, 小细胞肺, 放射治疗, 局限期

Abstract: Small cell lung cancer (SCLC) presents the characteristics of high malignant degree and distant metastasis. About 25%～30% of the patients with SCLC are confirmed to be limited stage (LS) SCLC at first visit. Early chest radiotherapy should be a better option for the timing of radiotherapy for LSSCLC, EP scheme (etoposide + cisplatin) chemotherapy combined with radiotherapy is acceptable for the sequence of radiotherapy and chemotherapy. CT, MRI, PET imaging visible tumors should be considered as the radiotherapy targets. Radiation dose and segmentation methods should be improved total dose of radiation or altered fractionated radiotherapy. Prophylactic cranial irradiation can improve the 3year survive and reduce brain metastasis rate of patients with LSSCLC.

Key words: Carcinoma, non-small-cell lung, Radiotherapy, Limitedstage