微小RNA与肺癌

doi:10.3760/cma.j.issn.1673-422X.2015.02.017

国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (2): 144-146.doi: 10.3760/cma.j.issn.1673-422X.2015.02.017

微小RNA与肺癌

向敏,朱玲,陈艳,刘馨,王熙才

650118 昆明医科大学第三附属医院肿瘤研究所；云南省肿瘤医院肿瘤研究所

出版日期:2015-02-08 发布日期:2015-02-02
通讯作者: Wang Xicai E-mail:wangxc2005323@126.com
基金资助:
国家自然科学基金（81460358)；云南省卫生科技基金（2012WS041）;云南省孔祥复院士基金

microRNAs and lung cancer

Xiang Min, Zhu Ling, Chen Yan, Liu Xin, Wang Xicai

Cancer Institute, Third Affiliated Hospital of Kunming Medical College, Cancer Institute of Yunnan Tumor Hospital, Kunming 650118, China

Online:2015-02-08 Published:2015-02-02
Contact: 王熙才 E-mail:wangxc2005323@126.com

摘要/Abstract

摘要： 微小RNA（miRNA）是短的非编码蛋白质的RNA，其在细胞增殖、分化、凋亡以及致癌和抗癌信号激活中起重要作用。研究表明，miRNA的异常表达与肺癌的发生、组织学类型、诊断、治疗和预后密切相关，其可能成为肺癌最有潜力和前途的治疗靶点。

关键词: 微RNAs, 肺肿瘤

Abstract: microRNAs (miRNAs) are short nonproteincoding RNAs, which play important roles in the cell proliferation, differentiation, apoptosis, as well as activation of oncogenic and antioncogenic signals. Researches show that the abnormal expressions of miRNAs are closely related to the tumorigenesis, histological type, diagnosis, treatment and prognosis of lung cancer. So miRNAs may be the most potential and promising therapeutic targets for lung cancer.

Key words: MicroRNAs, Lung neoplasms

向敏,朱玲,陈艳,刘馨,王熙才. 微小RNA与肺癌[J]. 国际肿瘤学杂志, 2015, 42(2): 144-146.

Xiang Min, Zhu Ling, Chen Yan, Liu Xin, Wang Xicai. microRNAs and lung cancer[J]. Journal of International Oncology, 2015, 42(2): 144-146.

参考文献

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微小RNA与肺癌

microRNAs and lung cancer

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