国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (3): 200-202.

• 综述 • 上一篇    下一篇

乳腺癌与甲状腺疾病的关系

温芬, 朱丽萍   

  1. 830011乌鲁木齐,新疆医科大学附属肿瘤医院乳腺外科

  • 出版日期:2013-03-08 发布日期:2013-02-25
  • 通讯作者: 朱丽萍,E-mail: E-mail:zlp_1005@sina.com

Breast cancer and thyroid diseases

WEN Fen,ZHU Li-Ping   

  1. Department of Breast Surgery, the Affiliated Cancer Hospital of Xinjiang Medical University, Urumchi 830011, China

  • Online:2013-03-08 Published:2013-02-25
  • Contact: ZHU Li-ping, E-mail: zlp_1005@sina.com E-mail:zlp_1005@sina.com

摘要: 甲状腺激素及相关抗体在乳腺癌疾病自然发展过程中具有一定作用,可能的机制包括碘复合物抑制乳腺细胞增殖和促进其凋亡;甲状腺激素可影响乳腺癌细胞的增殖与凋亡;甲状腺激素与雌激素的比例失调,促进乳腺细胞癌变;甲减可影响乳腺肿瘤的增殖和侵袭力;甲状腺疾病时淋巴细胞浸润或局部免疫反应异常等。

关键词: 乳腺肿瘤, 甲状腺肿瘤, 甲状腺激素类

Abstract: Thyroid hormones and the related antibodies have some function in the natural process of breast cancer development. The possible mechanisms include: iodine complex can inhibit breast cell proliferation and can induce apoptosis; thyroid hormone can affect breast cancer cell proliferation and apoptosis; the imbalance of thyroid hormone and estrogen hormone promotes breast cells cancerous; hypothyroidism may affect the proliferation and invasiveness of breast tumors; lymphocytic infiltration or abnormal local immune response in thyroid disease.

Key words: Breast neoplasms, Thyroid neoplasms, Thyroid hormones