国际肿瘤学杂志 ›› 2012, Vol. 39 ›› Issue (7): 513-515.

• 综述 • 上一篇    下一篇

小胶质细胞在脑转移癌中的作用

李燕,白鹰   

  1. 大连大学附属新华医院神经内三科
  • 出版日期:2012-08-06 发布日期:2012-08-06
  • 通讯作者: 白鹰,E-mail: yingbai@yahoo.cn E-mail:yingbai@yahoo.cn

Microglia in brain metastasis tumor

 LI  Yan, BAI  Ying   

  1. Department of Neurology, Xinhua Hospital, Dalian University, Dalian 116021, China
  • Online:2012-08-06 Published:2012-08-06
  • Contact: BAI Ying, E-mail: yingbai@yahoo.cn E-mail:yingbai@yahoo.cn

摘要: 小胶质细胞(MG)是中枢神经系统损伤和疾病中主要的免疫效应细胞,可以通过多种途径调节脑转移癌(BMT)的发生发展。研究MG在BMT发生发展中的作用及机制将为BMT的预防及治疗提供新思路。

关键词: 小神经胶质细胞, 脑肿瘤, 一氧化氮, 肿瘤坏死因子α, 内皮缩血管肽-1

Abstract: Microglia (MG) is recognized as the main immune effector in central nervous system injury and disease. MG can regulate the tumorigenesis and development of brain metastases tumor (BMT) by different ways. Studing the roles and mechanisms of MG in BMT will provide new insights into the prevention and treatment of BMT.

Key words: Microglia, Brain neoplasms, Nitric oxide, Tumor necrosis factor-alpha, Endothelin-1