[1] Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012[J
]. CA Cancer J Clin, 2015, 65(2): 87-108. DOI: 10.3322/caac.21262.
[2] Torre LA, Siegel RL, Ward EM, et al. Global cancer incidence and
mortality rates and trends—an update[J]. Cancer Epidemiol Biomarkers
Prev, 2016, 25(1): 16-27. DOI: 10.1158/10559965.EPI150578.
[3] Shen J, Wei J, Wang H, et al. A threegene signature as potential
predictive biomarker for irinotecan sensitivity in gastric cancer[J]. J
Transl Med, 2013, 11: 73. DOI: 10.1186/147958761173.
[4] Jeong SH, Han JH, Kim JH, et al. Bax predicts outcome in gastric
cancer patients treated with 5fluorouracil, leucovorin, and oxaliplatin
palliative chemotherapy[J]. Dig Dis Sci, 2011, 56(1): 131-138. DOI:
10.1007/s1062001012808.
[5] Qiu M, Zhou Y, Zhang X, et al. Lauren classification combined with
HER2 status is a better prognostic factor in Chinese gastric cancer
patients[J]. BMC Cancer, 2014, 14: 823. DOI: 10.1186/1471240714823.
[6] Tan IB, Ivanova T, Lim KH, et al. Intrinsic subtypes of gastric can
cer, based on gene expression pattern, predict survival and respond
differently to chemotherapy[J]. Gastroenterology, 2011, 141(2): 476-485,
485.e111. DOI: 10.1053/j.gastro.2011.04.042.
[7] Lee HJ, Nam KT, Park HS, et al. Gene expression profiling of
metaplastic lineages identifies CDH17 as a prognostic marker in early stage
gastric cancer[J]. Gastroenterology, 2010, 139(1): 213-225.e3. DOI:
10.1053/j.gastro.2010.04.008.
[8] Wang J, Yu JC, Kang WM, et al. The predictive effect of cadherin17
on lymph node micrometastasis in pN0 gastric cancer[J]. Ann Surg Oncol,
2012, 19(5): 1529-1534. DOI: 10.1245/s1043401121153.
[9] Wang J, Kang WM, Yu JC, et al. Cadherin17 induces tumorigenesis and
lymphatic metastasis in gastric cancer through activation of NFκB
signaling pathway[J]. Cancer Biol Ther, 2013, 14(3): 262270. DOI:
10.4161/cbt.23299.
[10] Choong ML, Tan SH, Tan TZ, et al. Molecular integrative clustering
of Asian gastric cell lines revealed two distinct chemosensitivity clusters
[J]. PLoS One, 2014, 9(10): e111146. DOI: 10.1371/journal.pone.0111146.
[11] Chen K, Yang D, Li X, et al. Mutational landscape of gastric
adenocarcinoma in Chinese: implications for prognosis and therapy[J].
Proc Natl Acad Sci USA, 2015, 112(4): 1107-1112. DOI:
10.1073/pnas.1422640112.
[12] Lei Z, Tan IB, Das K, et al. Identification of molecular subtypes of
gastric cancer with different responses to PI3kinase inhibitors and
5fluorouracil[J]. Gastroenterology, 2013, 145(3): 554-565. DOI:
10.1053/j.gastro.2013.05.010.
[13] Bass AJ, Thorsson V, Shmulevich I, et al. Comprehensive molecular
characterization of gastric adenocarcinoma[J]. Nature, 2014, 513(7517):
202-209. DOI: 10.1038/nature13480.
[14] Lee J, Van Hummelen P, Go C, et al. Highthroughput mutation
profiling identifies frequent somatic mutations in advanced gastric
adenocarcinoma[J]. PLoS One, 2012, 7(6): e38892. DOI:
10.1371/journal.pone.0038892.
[15] Sukawa Y, Yamamoto H, Nosho K, et al. Alterations in the human
epidermal growth factor receptor 2phosphatidylinositol 3kinasevAkt
pathway in gastric cancer[J]. World J Gastroenterol, 2012, 18(45): 6577-
6586. DOI: 10.3748/wjg.v18.i45.6577.
[16] Sawada T, Yashiro M, Sentani K, et al. New molecular staging with G
factor supplements TNM classification in gastric cancer: a multicenter
collaborative research by the Japan Society for Gastroenterological
Carcinogenesis GProject committee[J]. Gastric Cancer, 2015, 18(1): 119
-128. DOI: 10.1007/s1012001403382
[17] Cristescu R, Lee J, Nebozhyn M, et al. Molecular analysis of gastric
cancer identifies subtypes associated with distinct clinical outcomes[J].
Nat Med, 2015, 21(5): 449-456. DOI: 10.1038/nm.3850
[18] Wang K, Kan J, Yuen ST, et al. Exome sequencing identifies frequent
mutation of ARID1A in molecular subtypes of gastric cancer[J]. Nat Genet,
2011, 43(12): 1219-1223. DOI: 10.1038/ng.982
[19] Li Y, Li A, Glas M, et al. cMet signaling induces a reprogramming
network and supports the glioblastoma stemlike phenotype[J]. Proc Natl
Acad Sci USA, 2011, 108(24): 99519956. DOI: 10.1073/pnas.1016912108.
[20] Singh A, Settleman J. EMT, cancer stem cells and drug resistance: an
emerging axis of evil in the war on cancer[J]. Oncogene, 2010, 29(34):
4741-4751. DOI: 10.1038/onc.2010.215.
[21] Loboda A, Nebozhyn MV, Watters JW, et al. EMT is the dominant
program in human colon cancer[J]. BMC Med Genomics, 2011, 4: 9. DOI:
10.1186/1755879449.
[22] Pino MS, Kikuchi H, Zeng M, et al. Epithelial to mesenchymal
transition is impaired in colon cancer cells with microsatellite
instability[J]. Gastroenterology, 2010, 138(4): 1406-1417. DOI:
10.1053/j.gastro.2009.12.010.
[23] Roepman P, Schlicker A, Tabernero J, et al. Colorectal cancer
intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair
and epithelialtomesenchymal transition[J]. Int J Cancer, 2014, 134
(3): 552-562. DOI: 10.1002/ijc.28387.
[24] Cho JY, Lim JY, Cheong JH, et al. Gene expression signaturebased
prognostic risk score in gastric cancer[J]. Clin Cancer Res, 2011, 17(7):
1850-1857. DOI: 10.1158/10780432.CCR102180.
[25] Deng N, Goh LK, Wang H, et al. A comprehensive survey of genomic
alterations in gastric cancer reveals systematic patterns of molecular
exclusivity and cooccurrence among distinct therapeutic targets[J].
Gut, 2012, 61(5): 673-684. DOI: 10.1136/gutjnl2011301839.
[26] Ueda T, Volinia S, Okumura H, et al. Relation between microRNA
expression and progression and prognosis of gastric cancer: a microRNA
expression analysis[J]. Lancet Oncol, 2010, 11(2): 136-146. DOI:
10.1016/S14702045(09)703432. |