术前影响胃癌患者预后的常用血液学指标

doi:10.3760/cma.j.issn.1673422X.2017.03.018

国际肿瘤学杂志 ›› 2017, Vol. 44 ›› Issue (3): 228-230.doi: 10.3760/cma.j.issn.1673422X.2017.03.018

术前影响胃癌患者预后的常用血液学指标

张宝营,崔静,姜雷,关泉林

730000 兰州大学第一医院肿瘤外科

出版日期:2017-03-08 发布日期:2017-02-28
通讯作者: 关泉林 E-mail:guanquanlin@163.com
基金资助:
甘肃省科技支撑计划（1504FKCA084）；甘肃省卫生行业科研计划

（GSWST201316）

Preoperative hematological indexes used to evaluate the prognosis of gastric cancer patients

Zhang Baoying, Cui Jing, Jiang Lei, Guan Quanlin.

Department of Oncological Surgery, First Hospital of Lanzhou University, Lanzhou 730000, China

Online:2017-03-08 Published:2017-02-28
Contact: Guan Quanlin E-mail:guanquanlin@163.com
Supported by:
Science and

Technology Support Project of Gansu Province (1504FKCA084); Health Industry

Scientific Research Project of Gansu Province (GSWST201316)

摘要/Abstract

摘要： 胃癌是我国高发肿瘤，其恶性程度高、死亡率高、预后差。血液学指标是术前常规检查，价格低廉。通过血液学指标（如肿瘤标志物、炎症指标等）可对胃癌患者肿瘤大小、浸润深度、淋巴结转移、复发情况进行整体评估，以更好地了解手术风险，采取预防措施，提高患者生存率。

关键词: 胃肿瘤 , 血液学 , 预后

Abstract: Gastric cancer is a highrisk tumor in China, with high malignant degree, high mortality and poor prognosis. Hematological indexes are preoperative routine examination with low prices. Hematological indexes (such as tumor markers, inflammation index, etc) can be used to overall evaluate tumor size, depth of invasion, lymph node metastasis and recurrence of gastric cancer patients, which are helpful for us to better understand the surgical risks, and take preventive measures and improve the survival rate.

Key words: Stomach neoplasms, Hematology, Prognosis

张宝营,崔静,姜雷,关泉林. 术前影响胃癌患者预后的常用血液学指标[J]. 国际肿瘤学杂志, 2017, 44(3): 228-230.

Zhang Baoying, Cui Jing, Jiang Lei, Guan Quanlin. . Preoperative hematological indexes used to evaluate the prognosis of gastric cancer patients[J]. Journal of International Oncology, 2017, 44(3): 228-230.

参考文献

［1］ Wang W, Chen XL, Zhao SY, et al. Prognostic significance of preoperative serum CA125, CA199 and CEA in gastric carcinoma［J］. Oncotarget, 2016, 7(23): 35423-35436. DOI: 10.18632/oncotarget.8770. ［2］张燕华, 李雁, 陈创, 等. 多种肿瘤标志物与胃癌进展及预后的关系［J］. 武汉大学学报: 医学版, 2009, 30(4): 455-458, 462. DOI: 10.14188/j.16718852.2009.04.031. ［3］ Lai IR, Lee WJ, Huang MT, et al. Comparison of serum CA724, CEA, TPA, CA199 and CA125 levels in gastric cancer patients and correlation with recurrence［J］. Hepatogastroenterology, 2002, 49(46): 1157-1160. ［4］ Yamashita H, Katai H. Systemic inflammatory response in gastric cancer［J］. World J Surg, 2010, 34(10): 2399-2400. DOI: 10.1007/s0026801007031. ［5］ Jiang Y, Xu H, Jiang H, et al. Pretreatment neutrophillymphocyte count ratio may associate with gastric cancer presence［J］. Cancer Biomark, 2016, 16(4): 523-528. DOI: 10.3233/CBM160593. ［6］石朋, 赵毅, 邓鑫. 术前中性粒细胞淋巴细胞比率(NLR)预测胃癌预后的临床意义［J］. 现代肿瘤医学, 2012, 20(5): 987-991. DOI: 10.3969/j.issn.16724992.2012.05.37. ［7］ Chen XL, Xue L, Wang W, et al. Prognostic significance of the combination of preoperative hemoglobin, albumin, lymphocyte and platelet in patients with gastric carcinoma: a retrospective cohort study［J］. Oncotarget, 2015, 6(38): 41370-41382. DOI: 10.18632/oncotarget.5629. ［8］ Xu L, Zhou X, Wang J, et al. The hematologic markers as prognostic factors in patients with resectable gastric cancer［J］. Cancer Biomark, 2016, 17(3): 359-367. DOI: 10.3233/cbm160648. ［9］ Sun X, Liu X, Liu J, et al. Preoperative neutrophiltolymphocyte ratio plus platelettolymphocyte ratio in predicting survival for patients with stage ⅠⅡ gastric cancer［J］. Chin J Cancer, 2016, 35(1): 57. DOI: 10.1186/s40880 01601222. ［10］ Liu X, Sun X, Liu J, et al. Preoperative Creactive protein/albumin ratio predicts prognosis of patients after curative resection for gastric cancer［J］. Transl Oncol, 2015, 8(4): 339-345. DOI: 10.1016/j.tranon.2015.06.006. ［11］ Ishino Y, Saigusa S, Ohi M, et al. Preoperative Creactive protein and operative blood loss predict poor prognosis in patients with gastric cancer after laparoscopyassisted gastrectomy［J］. Asian J Endosc Surg, 2014, 7(4): 287-294. DOI: 10.1111/ases.12126. ［12］ Liu BZ, Tao L, Chen YZ, et al. Preoperative body mass index, blood albumin and triglycerides predict survival for patients with gastric cancer ［J］. PLoS One, 2016, 11(6): e0157401. DOI: 10.1371/journal.pone.0157401. ［13］孙晓春. C反应蛋白与胃癌相关性的meta分析［D］ . 重庆: 重庆医科大学, 2014. ［14］李慕行, 毕新宇, 李智宇, 等. 格拉斯哥评分对肝细胞肝癌患者的预后影响的荟萃分析［J］. 肝癌电子杂志, 2015, 2(3): 31-36. ［15］ Zhang CX, Wang SY, Chen SQ, et al. Association between pretreatment Glasgow prognostic score and gastric cancer survival and clinicopathological features: a metaanalysis［J］. Onco Targets Ther, 2016, 9: 3883-3891. DOI: 10.2147/ ott.s103996. ［16］贺淑霞, 雷晓丽. 血浆纤维蛋白原水平与恶性肿瘤的生长转移关系［J］. 宁夏医学院学报, 2007, 29(5): 508-509. DOI: 10.3969/j.issn.16746309.2007.05.027. ［17］ Yu X, Hu F, Yao Q, et al. Serum fibrinogen levels are positively correlated with advanced tumor stage and poor survival in patients with gastric cancer undergoing gastrectomy: a large cohort retrospective study［ J］. BMC Cancer, 2016, 16(1): 480. DOI: 10.1186/s128850162510z. ［18］ Yamamoto M, Kurokawa Y, Miyazaki Y, et al. Usefulness of preoperative plasma fibrinogen versus other prognostic markers for predicting gastric cancer recurrence［J］. World J Surg, 2016, 40(8): 1904 -1909. DOI: 10.1007/s00268016 34745. ［19］ Tamura T, Inagawa S, Hisakura K, et al. Evaluation of serum highdensity lipoprotein cholesterol levels as a prognostic factor in gastric cancer patients［J］. J Gastroenterol Hepatol, 2012, 27(10): 1635- 1640. DOI: 10.1111/j.1440 1746.2012.07189.x. ［20］李旭哲, 刘斌正, 马雅静, 等. 胃癌患者术前血液中钾、钠、氯、镁、磷的相关性及其对生存预后的影响［J］. 中国现代医学杂志, 2016, 26(11): 34-39. DOI: 10.3969/ j.issn.10058982.2016.11.007.

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术前影响胃癌患者预后的常用血液学指标

Preoperative hematological indexes used to evaluate the prognosis of gastric cancer patients

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