国际肿瘤学杂志 ›› 2017, Vol. 44 ›› Issue (11): 864-865.doi: 10.3760/cma.j.issn.1673-422X.2017.11.015

• 综述 • 上一篇    下一篇

贝伐珠单抗治疗非小细胞肺癌脑转移

刘梦实,杨海燕,李红梅   

  1. 266000青岛大学附属医院肿瘤科
  • 收稿日期:2017-09-11 出版日期:2017-11-08 发布日期:2017-11-24
  • 通讯作者: 刘梦实 E-mail:obstriker@163.com

Bevacizumab in the treatment of non-small-cell lung cancer with brain metastases

Liu Mengshi, Yang Haiyan, Li Hongmei   

  1. Department of Oncology, Affiliated Hospital of Qingdao University, Qingdao 266000, China
  • Received:2017-09-11 Online:2017-11-08 Published:2017-11-24
  • Contact: Liu Mengshi E-mail:obstriker@163.com

摘要: 肺癌脑转移的发生影响患者预后,抗血管生成治疗成为继手术、全脑放疗、立体定位放疗和化疗之后肺癌脑转移患者新的治疗选择。贝伐珠单抗作为一种抗血管生成药物,具有较好的控制瘤周水肿的作用。研究表明,贝伐珠单抗联合化、放疗治疗非小细胞肺癌脑转移具有较好的疗效及安全性。

关键词: 癌, 非小细胞肺, 肿瘤转移, 贝伐珠单抗

Abstract: The occurrence of brain metastases in lung cancer affects the prognosis of patients. Following surgery, whole brain radiotherapy, stereotactic radiotherapy and chemotherapy, antiangiogenesis therapy has become a new treatment option for lung cancer patients with brain metastases. As an antiangiogenic drug, bevacizumab has a better effect of controlling peritumoral edema. Studies have shown that bevacizumab combined with chemotherapy, radiotherapy to treat nonsmall cell lung cancer with brain metastasis has a good efficacy and safety.

Key words: Carcinoma, non-small cell lung, Neoplasm metastases, Bevacizumab