国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (12): 932-935.doi: 10.3760/cma.j.issn.1673-422X.2015.12.013

• 综述 • 上一篇    下一篇

食管癌放疗增敏剂的临床研究

康梅,权循凤   

  1. 230022 合肥,安徽医科大学第一附属医院肿瘤放疗科
  • 出版日期:2015-12-08 发布日期:2015-11-10
  • 通讯作者: 权循凤 E-mail:xunfengquan@163.com
  • 基金资助:

    2010年高校省级自然科学研究科研基金(KJ2010A170)

Clinical study on the radiosensitizer of esophageal carcinoma

Kang Mei, Quan Xunfeng   

  1. Department of Radiation Oncology, First Affiliated Hospital of Anhui Medical University, Hefei 230022, China
  • Online:2015-12-08 Published:2015-11-10
  • Contact: Quan Xunfeng E-mail:xunfengquan@163.com

摘要: 放疗增敏剂作为一种新型抗肿瘤药物与放疗具有协同作用,能提高放射线对肿瘤细胞的杀伤率,增强放疗疗效。近年来由于新理论新技术的提出,放疗增敏剂的研究范围延伸至不同领域,取得了飞跃的发展,从传统的DNA靶点增敏剂到如今包括纳米微粒在内的新型放疗增敏剂。因此,放疗增敏剂联合放疗将作为一种新的食管癌治疗策略应用于临床,提高食管癌的治疗效果。

关键词: 食管肿瘤, 放射疗法, 辐射增敏药

Abstract: Radiosensitizer as a promising novel antitumor medicine has synergetic effects with radiotherapy, and can enhance the kill rate of tumor cells and radiotherapy effect. In recent years, due to the new theory and technology, the researches of radiosensitizer extend to different fields, from the traditional DNA target sensitizer to new radiosensitizer including nanoparticles. Consequently, radiosensitizer combined with radiotherapy will become a new and effective treatment strategy for esophageal carcinoma to enhance the therapeutic effect of esophageal carcinoma.

Key words: Esophageal neoplasms, Radiotherapy, Radiation-sensitizing agents