国际肿瘤学杂志 ›› 2017, Vol. 44 ›› Issue (3): 224-227.doi: 10.3760/cma.j.issn.1673422X.2017.03.017

• 综述 • 上一篇    下一篇

胃癌的分子分型研究进展

王炳智,薛丽燕,吕宁   

  1. 100021 国家癌症中心 /中国医学科学院北京协和医学院肿瘤医院病理科住院医师规范化培训基地
  • 出版日期:2017-03-08 发布日期:2017-02-28
  • 通讯作者: 吕宁 E-mail: nlu03@126.com
  • 基金资助:

     国家自然科学基金(81402463);北京希望马拉松专项基金(LC2015A03

Molecular classification of gastric cancer

Wang Bingzhi, Xue Liyan, Lyu Ning   

  1. Department of Pathology and Resident Training Base, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
  • Online:2017-03-08 Published:2017-02-28
  • Contact: Lyu Ning E-mail: nlu03@126.com
  • Supported by:

    National Natural Science Foundation

    of China (81402463); Beijing Marathon of Hope Foundation (LC2015A03)

摘要: 胃癌具有高度异质性,传统的组织病理学分型对临床工作的指导意义十分有 限。随着分子检测技术的飞速发展,以各种分子为依据进行的分型能够对胃癌的临床 治疗与预后提供更精准的帮助。胃癌分子分型包括Tan分型、Lei分型、克隆性分型、 癌症基因组图集(TCGA)分型和亚洲癌症研究组织(ACRG)分型等,这些分型各具特色 ,各有优劣。

关键词: 胃肿瘤, 分子分型

Abstract: Gastric cancer has high heterogeneity, and the traditional histopathologic classification has a limited significance for clinical work. Along with the dramatic development of molecular detection technology, it may be much more helpful for the treatment and prognosis to use the molecular classifications. Recently, there have been many researches on the molecular classification of gastric cancer, such as Tan type, Lei type, clonality type, The Cancer Genome Atlas (TCGA) type, Asian Cancer Research Group (ACRG) type, and so on. All of these molecular classification methods have respective advantages and disadvantages.

Key words: Stomach neoplasms, Molecular classification