国际肿瘤学杂志 ›› 2026, Vol. 53 ›› Issue (10): 635-640.doi: 10.3760/cma.j.cn371439-20250919-00100

• 综述 • 上一篇    

免疫检查点抑制剂在胃癌中的研究进展

闵希赟1, 马抓喜吉1, 关泉林2()   

  1. 1 兰州大学第一医院(第一临床医学院), 兰州 730000
    2 兰州大学第一医院肿瘤外科, 兰州 730000
  • 收稿日期:2025-09-19 出版日期:2026-10-08 发布日期:2026-10-10
  • 通讯作者: 关泉林,Email:guanql@lzu.edu.cn

Research progress of immune checkpoint inhibitors in gastric cancer

Min Xiyun1, Ma Zhuaxiji1, Guan Quanlin2()   

  1. 1 First Hospital of Lanzhou University (First School of Clinical Medicine), Lanzhou 730000, China
    2 Department of Surgical Oncology, First Hospital of Lanzhou University, Lanzhou 730000, China
  • Received:2025-09-19 Online:2026-10-08 Published:2026-10-10
  • Contact: Guan Quanlin,Email:guanql@lzu.edu.cn

摘要:

胃癌作为严重威胁人类健康的重大疾病,目前主要治疗手段仍为手术联合化疗。近年来,随着肿瘤免疫研究的深入,免疫检查点抑制剂在胃癌治疗中展现出显著疗效。免疫检查点抑制剂单药及联合治疗方案为胃癌患者提供了更多选择,显示出巨大的治疗潜力。对胃癌免疫检查点抑制剂的研究进展进行总结与探讨,能为临床更好地治疗胃癌提供新思路。

关键词: 胃肿瘤, 免疫检查点抑制剂, 免疫疗法

Abstract:

Gastric cancer is a major disease that poses a serious threat to human health. Currently,the primary treatment methods remain surgery combined with chemotherapy. In recent years,with the deepening of tumor immunology research,immune checkpoint inhibitors have shown significant efficacy in the treatment of gastric cancer. Both monotherapy and combination treatment regimens provide more options for patients with gastric cancer,demonstrating substantial therapeutic potential. Summarizing and discussing the research progress of immune checkpoint inhibitors in gastric cancer can offer new insights for better clinical management of the disease.

Key words: Stomach neoplasms, Immune checkpoint inhibitors, Immunotherapy