Abstract: The early diagnosis of breast cancer is crucial for improving the prognosis of patients. Some new diagnostic techniques can improve the early diagnosis rate. Studies show that microRNA, proteins in salivary, urinary polyamines could be used as novel tumor markers, with high sensitivities and specificities. With the help of optical technology and computers, the traditional diagnostic imaging technique also make a great breakthrough. Currently, image-guided minimally invasive biopsy techniques such as core needle biopsy and vacuum assisted biopsy have the advantages of accuracy, economy and little trauma, and can provide more samples, which have been widely applied in clinical practice.

Key words: Breast neoplasms, Early diagnosis