Journal of International Oncology ›› 2012, Vol. 39 ›› Issue (7): 516-518.

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Cadherins and triple-negative breast cancer

SHI Xue-Bing, WANG Lu   

  1. Department of Medical Oncology, Yijishan Hospital of Wannan Medical College, Wuhu 241000, China
  • Online:2012-08-06 Published:2012-08-06
  • Contact: WANG Lu, E-mail: lucyyjs@163.com E-mail:lucyyjs@163.com

Abstract: Cadherins that mediate the adhesion of the same type of cells by specific binding to calciumdependent adhesions of the same type with cadherins mainly consist of three subtypes including E-cadherin, P-cadherin and N-cadherin. In recent years, more and more studies have indicated that cadherins are closely related to triple-negative breast cancer (TNBC) and play an important role in prognosis and treatment of TNBC.

Key words: Cadherins, Breast neoplasms