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Journal of International Oncology ›› 2026, Vol. 53 ›› Issue (8): 502-507.doi: 10.3760/cma.j.cn371439-20250929-00081

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Research progress of tumor microenvironment in the pathogenesis of prostate cancer

Che Yunan, Chen Xiang, Chu Xu, Lu Daofeng, Jiang Kun()   

  1. Department of UrologyMa'anshan People's HospitalMa'anshan 243000, China
  • Received:2025-09-29 Online:2026-08-08 Published:2026-07-21
  • Contact: Jiang Kun, Email: 61411699@qq.com E-mail:61411699@qq.com
  • Supported by:
    Construction Project of Key Clinical Specialty in Ma′anshan City(Maweijian〔2025〕50)

Abstract:

Prostate cancer is a highly heterogeneous disease with a complex cellular ecosystem in the tumor microenvironment. The tumor microenvironment plays a crucial role in the occurrence and development of prostate cancer. Given its significant function in supporting tumor tissues growth, related research is increasingly focusing on this field. Relevant studies have shown that cellular and functional heterogeneity in the tumor microenvironment can promote the development of more effective disease treatment strategies. In particular, the interaction and co-evolution of tumor tissues and host cells in the tumor microenvironment can lead to novel therapeutic combination models that have great potential for treating and ultimately curing tumors.

Key words: Prostatic neoplasms, Tumor microenvironment, Tumor cells