国际肿瘤学杂志 ›› 2012, Vol. 39 ›› Issue (11): 867-869.

• 综述 • 上一篇    下一篇

微小RNA与胰腺癌侵袭性转移的研究进展

李沛, 王铮   

  1. 710061 西安交通大学医学院第一附属医院肝胆外科
  • 出版日期:2012-11-08 发布日期:2012-11-16
  • 通讯作者: 王铮,E-mail: zheng.wang11@mail.xjtu.edu.cn E-mail:zheng.wang11@mail.xjtu.edu.cn

microRNA in pancreatic cancer invasive metastasis

LI  Pei, WANG  Zheng   

  1. Department of Hepatobiliary Surgery, First Affiliated Hospital, Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, 710061,China
  • Online:2012-11-08 Published:2012-11-16
  • Contact: Corresponding author:WANG Zheng, E-mail: zheng.wang11@mail.xjtu.edu.cn E-mail:zheng.wang11@mail.xjtu.edu.cn

摘要: 胰腺癌恶性侵袭转移能力很强,其机制仍未完全明确。近年来有研究发现微小RNA(miRNA)影响胰腺癌发生发展,并与其转移密切相关。与胰腺癌转移相关的miRNA作用机制的揭示,将会为胰腺癌的治疗提供新的途径。

关键词: 微RNAs, 胰腺肿瘤, 肿瘤浸润, 肿瘤转移

Abstract: Pancreatic cancer has a strong ability of invasive and metastasis, and the mechanism is still not completely clear. It has been demonstrated that aberrant expression of microRNAs(miRNA) is closely associated with the occurrence, development and metastasis of pancreatic cancer.The reveal of miRNA mechanism related to the metastasis of pancreatic cancer would provide a new approach to the treatment of pancreatic cancer.

Key words: MicroRNAs, Pancrestic neoplasms, Neoplasm invasiveness, Neoplasm metastasis