国际肿瘤学杂志 ›› 2024, Vol. 51 ›› Issue (3): 170-174.doi: 10.3760/cma.j.cn371439-20231130-00027

• 综述 • 上一篇    下一篇

寡转移非小细胞肺癌的放疗进展

李书月, 马辰莺, 周菊英(), 徐晓婷, 秦颂兵   

  1. 苏州大学附属第一医院放疗科,苏州 215006
  • 收稿日期:2023-11-30 修回日期:2024-01-03 出版日期:2024-03-08 发布日期:2024-04-10
  • 通讯作者: 周菊英,Email: zhoujuyingsy@163.com
  • 基金资助:
    国家自然科学基金(81602792)

Progress of radiotherapy in oligometastatic non-small cell lung cancer

Li Shuyue, Ma Chenying, Zhou Juying(), Xu Xiaoting, Qin Songbing   

  1. Department of Radiation Oncology, First Affiliated Hospital of Soochow University, Suzhou 215006, China
  • Received:2023-11-30 Revised:2024-01-03 Online:2024-03-08 Published:2024-04-10
  • Contact: Zhou Juying, Email: zhoujuyingsy@163.com
  • Supported by:
    National Natural Science Foundation of China(81602792)

摘要:

对寡转移非小细胞肺癌(NSCLC)进行有效的局部治疗,可延长患者生存期。放疗作为局部治疗手段之一,在NSCLC寡转移患者的治疗中是作为一线治疗还是巩固治疗使用目前尚未定论。多项研究表明立体定向消融放疗可在不增加不良反应的前提下为寡转移NSCLC患者带来临床获益。此外,放疗与免疫治疗联合能否进一步延长寡转移NSCLC患者无进展生存期及总生存期的相关探索也值得关注。

关键词: 癌, 非小细胞肺, 肿瘤转移, 放射疗法, 计算机辅助

Abstract:

The effective local management of oligometastatic non-small cell lung cancer (NSCLC) has the potential to prolong patients' survival. The role of radiotherapy as a local treatment modality in patients with oligometastatic NSCLC, whether as first-line therapy or consolidation therapy, remains uncertain. Several studies have demonstrated that stereotactic ablative radiotherapy can offer clinical benefits for patients with oligometastatic NSCLC without increasing adverse reactions. Furthermore, the exploration of the potential synergistic effects of combining radiotherapy and immunotherapy on extending progression-free survival and overall survival in patients with oligometastatic NSCLC is also a topic worthy of attention.

Key words: Carcinoma, non-small-cell lung, Neoplasm metastasis, Radiotherapy, computer-assisted