小细胞肺癌免疫治疗预后预测指标研究进展

doi:10.3760/cma.j.cn371439-20230105-00035

摘要/Abstract

摘要：

免疫检查点抑制剂的出现为小细胞肺癌患者带来了新的希望。研究发现PD-L1表达、肿瘤突变负荷、基因组特征、外周血指标等可作为接受免疫治疗的小细胞肺癌患者的预后预测指标。进一步探索评估相关预测指标，可为筛选免疫治疗潜在获益患者提供参考。

Abstract:

The emergence of immune checkpoint inhibitors holds new promise for patients with small cell lung cancer. Studies have found that PD-L1 expression， tumor mutation burden， genomic characteristics， peripheral blood parameters and other indicators can be used as prognostic predictors in patients with small cell lung cancer receiving immunotherapy. Further exploration and evaluation of relevant predictors can provide a reference for screening patients with potential benefits of immunotherapy.

Key words: Small cell lung carcinoma, Immune checkpoint inhibitors, Prognosis, Predictors

王雅倩, 杜逸玮, 王兴, 贾军梅. 小细胞肺癌免疫治疗预后预测指标研究进展[J]. 国际肿瘤学杂志, 2023, 50(3): 179-182.

Wang Yaqian, Du Yiwei, Wang Xing, Jia Junmei. Prognostic predictors of immunotherapy in patients with small cell lung cancer[J]. Journal of International Oncology, 2023, 50(3): 179-182.

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