国际肿瘤学杂志 ›› 2026, Vol. 53 ›› Issue (3): 178-181.doi: 10.3760/cma.j.cn371439-20250719-00029

• 综述 • 上一篇    下一篇

精准医学时代的肿瘤化疗进展

张百红1, 岳红云2()   

  1. 1解放军联勤保障部队第九四〇医院肿瘤科,兰州 730050
    2解放军联勤保障部队第九四〇医院眼科,兰州 730050
  • 收稿日期:2025-07-19 出版日期:2026-03-08 发布日期:2026-02-09
  • 通讯作者: 岳红云,Email: yhyophthalmologist@163.com

Advances in cancer chemotherapy in the era of precision medicine

Zhang Baihong1, Yue Hongyun2()   

  1. 1Department of Oncology,940th Hospital of Joint Logistics Support Force of People's Liberation Army,Lanzhou 730050,China
    2Department of Ophthalmology,940th Hospital of Joint Logistics Support Force of People's Liberation Army,Lanzhou 730050,China
  • Received:2025-07-19 Online:2026-03-08 Published:2026-02-09

摘要:

化疗是肿瘤系统治疗的基石。在精准医学时代,基因监控和模型预测可监测化疗药物反应和毒性并指导临床医生选择合理的治疗方案,纳米传输可降低化疗药物的毒性和治疗抵抗,抗体偶联可直接将化疗药物精准靶向肿瘤细胞,共同促进肿瘤的精准化疗,人工智能和机器学习将进一步推动肿瘤精准化疗的发展。

关键词: 肿瘤, 精准医学, 药物疗法

Abstract:

Chemotherapy remains the cornerstone of systemic treatment for tumors. In the era of precision medicine,gene monitoring and model prediction can monitor the response and toxicity of chemotherapy drugs and guide clinicians in choosing appropriate treatment plans. Nanotechnology delivery can reduce the toxicity and treatment resistance of chemotherapy drugs. Antibody conjugation can directly target chemotherapy drugs to tumor cells with precision,thus jointly promoting precise chemotherapy for tumors. Artificial intelligence and machine learning will further drive the development of precise chemotherapy for tumors.

Key words: Neoplasms, Precision medicine, Drug therapy