腮腺保护在头颈部肿瘤放疗中的研究进展

doi:10.3760/cma.j.issn.1673422X.2015.09.013

摘要/Abstract

摘要： 放疗是头颈部肿瘤最主要的治疗手段，但会导致相邻组织的损害，其中放射性口干症是最常见的并发症。放疗所致腮腺损伤机制目前尚不清楚。腮腺功能的检测包括测量唾液流量与唾液流率、腮腺单光子发射计算机断层成像术（SPECT）、CT及磁共振成像（MRI）等。如何保护腮腺成为近年来研究的热点。目前保护腮腺的方法主要有放疗方式的选择、放疗计划的优化、药物、干细胞移植、基因转导。

Abstract: Radiotherapy is the main treatment for head and neck cancer, but it will result in adjacent tissue damage,including radioactive xerostomia,the most common complication.The mechanism of radiationinduced parotid damage injury is unclear. Parotid function test include detection of parotid salivary flow and salivary flow rate, parotid SPECT, CT and MRI, etc.How to protect the parotid glands becomes a hot research in recent years.At present,the main methods of protecting the parotid glands includes selecting patterns of radiotherapy,radiotherapy planning optimization,drugs，stem cell transplantation and gene transduction.

刘娟, 马代远. 腮腺保护在头颈部肿瘤放疗中的研究进展[J]. 国际肿瘤学杂志, 2015, 42(8): 689-.

LIU Juan, MA Dai-Yuan. Research progress in radiotherapy for head and neck tumors in parotid gland protection[J]. Journal of International Oncology, 2015, 42(8): 689-.

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