国际肿瘤学杂志

国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (4): 267-270.doi: 10.3760/cma.j.issn.1673422X.2014.04.009

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甲状腺癌的流行现状及危险因素

曹龄之, 谢建平, 彭小东   

  1. 637000 南充，川北医学院附属医院核医学科
  • 出版日期:2014-04-08 发布日期:2014-03-17
  • 通讯作者: 谢建平，Email: xjp2262227@163.com E-mail:xjp2262227@163.com

Prevalence and risk factors of thyroid carcinoma

 CAO  Ling-Zhi, XIE  Jian-Ping, PENG  Xiao-Dong   

  1. Department of Nuclear Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China
  • Online:2014-04-08 Published:2014-03-17
  • Contact: Xie Jianping E-mail:xjp2262227@163.com

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1188

被引次数

11

摘要： 甲状腺癌的发病与多种因素有关，辐射是明确的危险因素，碘摄取量与甲状腺癌的关系仍存在争议。研究表明，多个信号传导通路中遗传学和表观遗传学的改变是甲状腺癌分子致病机制的核心。另外，促甲状腺素、体重指数和慢性淋巴细胞性甲状腺炎也与甲状腺癌的发生有关。

关键词: 甲状腺肿瘤, 发病率, 危险因素

Abstract: The incidence of thyroid carcinoma is associated with a variety of factors. Radiation is the clear risk factor, the relationship between iodine intake and thyroid carcinoma remains controversial. Researches show that the genetic and epigenetic changes of many signaling pathways are the key of molecular pathogenetic mechanism of thyroid carcinoma. In addition, thyroid stimulating hormone, body mass index and chronic lymphocytic thyroiditis are also associated with thyroid carcinoma.

Key words: Thyroid neoplasms, Incidence, Risk factors