国际肿瘤学杂志

国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (8): 695-698.

• 综述 • 上一篇    下一篇

分子靶向药物在肝细胞癌中的应用

孙海凤, 阮之平, 姚煜   

  1. 710061西安，陕西省肿瘤医院内三科（孙海凤）；西安交通大学医学院附属第一医院肿瘤科（阮之平、姚煜）
  • 出版日期:2013-09-08 发布日期:2013-09-16
  • 通讯作者: 通信作者：姚煜，E-mail: 13572101611@163.com E-mail:13572101611@163.com

Applications of molecular targeted drugs in hepatocellular carcinoma

SUN  Hai-Feng, RUAN  Zhi-Ping, YAO  Yu   

  1. Third Department of Medicine, Tumor Hospital of Shanxi Province, Xi′an 710061, China
  • Online:2013-09-08 Published:2013-09-16
  • Contact: Corresponding author: YAO Yu, E-mail: 13572101611@163.com E-mail:13572101611@163.com

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摘要： 手术切除和肝移植仍然是肝细胞癌（HCC）的治疗首选。对于不适宜手术切除的晚期HCC，传统的化疗并不能改善患者的预后。分子靶向药物的出现为晚期HCC的治疗提供了新的治疗手段。多靶点抑制剂、血管内皮生长抑制剂、单克隆抗体等分子靶向药物已经在肝细胞癌中广泛研究和应用。

关键词: 癌, 肝细胞, 分子靶向药物

Abstract: Surgical resection and liver transplantation are still the preferred treatments for patients with hepatocellular carcinoma (HCC). For the patients with advanced HCC which are not suitable for surgical resection, traditional chemotherapy can not improve the prognosis. Molecular targeted therapy is a new method and tendency in the treatment of HCC. Multiple targets inhibitors, vascular endothelial growth factor inhibitors and monoclonal antibodies for HCC are widely researched and applied.

Key words: Carcinoma, hepatocellular, Molecular targeted drugs