国际肿瘤学杂志

国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (4): 270-272.doi: 10.3760/cma.j.issn.1673422X.2014.04.010

• 综述 • 上一篇    下一篇

乳腺癌的分子分型

张百红, 岳红云   

  1. 730050 兰州军区兰州总医院肿瘤科（张百红），眼科（岳红云）
  • 出版日期:2014-04-08 发布日期:2014-03-17
  • 通讯作者: 张百红，Email: bhzhang1999@126.com E-mail:bhzhang1999@126.com

Prevalence and risk factors of thyroid carcinoma

ZHANG  Bai-Hong, YUE  Hong-Yun   

  1. Department of Oncology, Lanzhou General Hospital of Lanzhou Military Area Command, Lanzhou 730050, China
  • Online:2014-04-08 Published:2014-03-17
  • Contact: Zhang Baihong E-mail:bhzhang1999@126.com

PDF

1782

被引次数

102

摘要： 甲状腺癌的发病与多种因素有关，辐射是明确的危险因素，碘摄取量与甲状腺癌的关系仍存在争议。研究表明，多个信号传导通路中遗传学和表观遗传学的改变是甲状腺癌分子致病机制的核心。另外，促甲状腺素、体重指数和慢性淋巴细胞性甲状腺炎也与甲状腺癌的发生有关。

关键词: 甲状腺肿瘤, 发病率, 危险因素

Abstract: The incidence of thyroid carcinoma is associated with a variety of factors. Radiation is the clear risk factor, the relationship between iodine intake and thyroid carcinoma remains controversial. Researches show that the genetic and epigenetic changes of many signaling pathways are the key of molecular pathogenetic mechanism of thyroid carcinoma. In addition, thyroid stimulating hormone, body mass index and chronic lymphocytic thyroiditis are also associated with thyroid carcinoma.

Key words: Thyroid neoplasms, Incidence, Risk factors