国际肿瘤学杂志 ›› 2019, Vol. 46 ›› Issue (4): 248-252.doi: 10.3760/cma.j.issn.1673-422X.2019.04.012

• 综述 • 上一篇    下一篇

非小细胞肺癌放疗的进展与价值

高照,闫文星,刘林林   

  1. 吉林大学第二医院放疗科,长春  130041
  • 收稿日期:2019-03-04 修回日期:2019-03-19 出版日期:2019-04-08 发布日期:2019-05-29
  • 通讯作者: 刘林林,Email: 2660424632@qq.com E-mail:2660424632@qq.com

Progress and value of radiotherapy for non-small cell lung cancer

Gao Zhao, Yan Wenxing, Liu Linlin   

  1. Department of Radiotherapy, Second Affiliated Hospital of Jilin University, Changchun 130041, China
  • Received:2019-03-04 Revised:2019-03-19 Online:2019-04-08 Published:2019-05-29
  • Contact: Liu Linlin, Email: 2660424632@qq.com E-mail:2660424632@qq.com

摘要: 随着放疗设备的革新和靶向治疗、免疫治疗的推广应用,放疗在非小细胞肺癌(NSCLC)中的治疗模式和地位也不断改变。对于早期NSCLC,立体定向放疗可能成为手术的替代方法,但最佳分割模式仍需探索;对于可手术的局部晚期NSCLC患者,术后放疗仍存在争议,不可手术的患者同步放化疗后巩固免疫疗法结果令人鼓舞,预防性脑照射并不能改善患者生存。寡转移局部放疗有望延长患者生存期。

关键词: 癌, 非小细胞肺, 放射疗法, 治疗结果, 预后

Abstract: With the innovation of radiotherapy equipment and the promotion of targeted therapy and immunotherapy, the therapeutic mode and status of radiotherapy in non-small cell lung cancer (NSCLC) are constantly changing. For early NSCLC, stereotactic radiotherapy may be an alternative to surgery, but the optimal segmentation model still needs to be explored. As for locally advanced NSCLC, postoperative radiotherapy is still controversial for operable patients, the results of consolidated immunotherapy after concurrent chemoradiotherapy in inoperable patients are encouraging, prophylactic cranial irradiation does not improve survival. Local radiotherapy for patients with oligometastasis is expected to prolong survival.

Key words: Carcinoma, non-small-cell lung, Radiotherapy, Treatment outcome, Prognosis