表现为磨玻璃结节的早期肺腺癌的影像学、组织病理学及分子生物学特点

doi:10.3760/cma.j.issn.1673-422X.2018.10.011

摘要/Abstract

摘要： 随着多层螺旋CT应用于肺癌筛查工作，肺磨玻璃结节（GGN）得到了广泛关注。除了良性疾病，GGN常为早期肺腺癌及其癌前病变的特殊表现。因此，探索GGN的影像学特点与肺腺癌病理亚型及分子生物学之间的关系，对指导临床诊断与治疗具有重要意义。

关键词: 肺肿瘤, 体层摄影术, 螺旋计算机, 磨玻璃结节, 基因突变

Abstract: With multi-slice spiral CT widely used in lung cancer screening, groundglass nodule (GGN) has also received extensive attention. In addition to benign disease, GGN may also be a special manifestation of early lung adenocarcinoma and its precancerous lesions. Therefore, investigation of the correlation between CT imaging features of GGN and pathological subtypes or molecular biology of lung adenocarcinoma is of great significance in guiding clinical diagnosis and treatment.

Key words: Lung neoplasms, Tomography, spiral computed, Ground glass nodule, Gene mutation

马艺,许顺. 表现为磨玻璃结节的早期肺腺癌的影像学、组织病理学及分子生物学特点[J]. 国际肿瘤学杂志, 2018, 45(10): 627-631.

Ma Yi, Xu Shun. Pulmonary adenocarcinoma shown as groundglass nodule: radiology, histopathology and molecular biology characteristics[J]. Journal of International Oncology, 2018, 45(10): 627-631.

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