胸腺上皮性肿瘤手术治疗研究进展

doi:10.3760/cma.j.cn371439-20200224-00102

国际肿瘤学杂志 ›› 2020, Vol. 47 ›› Issue (11): 691-694.doi: 10.3760/cma.j.cn371439-20200224-00102

胸腺上皮性肿瘤手术治疗研究进展

唐焕雨¹, 黄桁¹, 姜凯元¹, 贺茜², 魏桢婷¹, 杨洁尘¹, 田东²()

¹川北医学院临床医学系,南充 637000
²川北医学院附属医院胸外科,南充 637000

收稿日期:2020-02-24 修回日期:2020-04-12 出版日期:2020-11-08 发布日期:2021-01-05
通讯作者: 田东 E-mail:22tiandong@163.com
基金资助:
国家级大学生创新创业训练计划(201910634007)

Research progress in surgical treatment of thymic epithelial tumors

Tang Huanyu¹, Huang Heng¹, Jiang Kaiyuan¹, He Xi², Wei Zhenting¹, Yang Jiechen¹, Tian Dong²()

¹Department of Clinical Medicine, North Sichuan Medicine College, Nanchong 637000, China
²Thoracic Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China

Received:2020-02-24 Revised:2020-04-12 Online:2020-11-08 Published:2021-01-05
Contact: Tian Dong E-mail:22tiandong@163.com
Supported by:
National Undergraduate Training Program for Innovation and Entrepreneurship(201910634007)

摘要/Abstract

摘要：

胸腺上皮性肿瘤是临床上最常见的前纵隔原发性肿瘤,目前仍以手术治疗为主。最早普遍采用胸骨正中切口切除肿瘤,但此术式会对患者造成较大的创伤。近年来微创手术的研究进展较快,由电视胸腔镜外科手术到被迅速推广的剑突下入路胸腔镜手术和机器人辅助胸腔镜手术。虽然各种手术方式之间的优劣及适应范围尚存争议,但目前已有大量研究证实微创手术具有更好的疗效及安全性。

关键词: 胸腺肿瘤, 胸腔镜, 机器人, 胸骨正中切口

Abstract:

Thymic epithelial tumor (TET) is the most common primary tumor of anterior mediastinum. Currently surgical treatment is still the main treatment. Median sternotomy is the first widely used method for tumor resection, but it will cause great trauma for patients. In recent years, the research on minimally invasive surgery has made rapid progress, from video-assisted thoracoscopic surgery to rapidly promoted subxiphoid approach video-assisted thoracoscopic surgery and robotic-assisted thoracic surgery. Although the advantages and disadvantages of various surgical methods and the scope of adaptation are still controversial, a large number of studies have confirmed that minimally invasive surgery has better efficacy and safety for TET.

Key words: Thymus neoplasms, Thoracoscopes, Robotics, Median sternotomy

唐焕雨, 黄桁, 姜凯元, 贺茜, 魏桢婷, 杨洁尘, 田东. 胸腺上皮性肿瘤手术治疗研究进展[J]. 国际肿瘤学杂志, 2020, 47(11): 691-694.

Tang Huanyu, Huang Heng, Jiang Kaiyuan, He Xi, Wei Zhenting, Yang Jiechen, Tian Dong. Research progress in surgical treatment of thymic epithelial tumors[J]. Journal of International Oncology, 2020, 47(11): 691-694.

参考文献 30

[1]	Maury JM, Girard N, Tabutin M, et al. Intra-Thoracic Chemo-Hyperthermia for pleural recurrence of thymoma[J]. Lung Cancer, 2017,108:1-6. DOI: 10.1016/j.lungcan.2017.02.014. doi: 10.1016/j.lungcan.2017.02.014 pmid: 28625619
[2]	Weissferdt A, Kalhor N, Bishop JA, et al. Thymoma: a clinicopathological correlation of 1470 cases[J]. Hum Pathol, 2018,73:7-15. DOI: 10.1016/j.humpath.2017.08.018. doi: 10.1016/j.humpath.2017.08.018 pmid: 28851660
[3]	Maurizi G, D'Andrilli A, Sommella L, et al. Transsternal thymec-tomy[J]. Thorac Cardiovasc Surg, 2015,63(3):178-186. DOI: 10.1055/s-0034-1396083. doi: 10.1055/s-0034-1396083 pmid: 25503818
[4]	许林. 恶性胸腺瘤的外科治疗[J]. 中国肿瘤外科杂志, 2017,9(2):69-71. DOI: 10.3969/j.issn.1674-4136.2017.02.001.
[5]	Marulli G, Comacchio GM, Schiavon M, et al. Comparing robotic and trans-sternal thymectomy for early-stage thymoma: a propensity score-matching study[J]. Eur J Cardiothorac Surg, 2018,54(3):579-584. DOI: 10.1093/ejcts/ezy075. doi: 10.1093/ejcts/ezy075 pmid: 29547970
[6]	Ruffini E, Filosso PL, Guerrera F, et al. Optimal surgical approach to thymic malignancies: new trends challenging old dogmas[J]. Lung Cancer, 2018,118:161-170. DOI: 10.1016/j.lungcan.2018.01.025. doi: 10.1016/j.lungcan.2018.01.025 pmid: 29571996
[7]	Suda T, Hachimaru A, Tochii D, et al. Video-assisted thoracoscopic thymectomy versus subxiphoid single-port thymectomy: initial results[J]. Eur J Cardiothorac Surg, 2016,49 Suppl 1: i54-i58. DOI: 10.1093/ejcts/ezv338.
[8]	Ercen E, Kılıç B, Kara HV, et al. Comparative study of video-assisted thoracoscopic surgery versus open thymectomy for thymoma and myasthenia gravis[J]. Wideochir Inne Tech Maloinwazyjne, 2018,13(3):376-382. DOI: 10.5114/wiitm.2018.75835. doi: 10.5114/wiitm.2018.75835 pmid: 30302151
[9]	Trivino A, Congregado M, Loscertales J, et al. Comparative analysis of video-assisted thoracic surgery versus open resection for early-stage thymoma[J]. Cir Esp, 2015,93(7):466-471. DOI: 10.1016/j.ciresp.2014.02.021. doi: 10.1016/j.ciresp.2014.02.021 pmid: 24882756
[10]	Zhang G, Li W, Chai Y, et al. Bilateral video-assisted thoracos-copic thymectomy for Masaoka stage ⅢA thymomas[J]. Thorac Cardiovasc Surg, 2015,63(3):206-211. DOI: 10.1055/s-0034-1395389. doi: 10.1055/s-0034-1395389 pmid: 25463359
[11]	Gonzalez-Rivas D, Wu CF, de la Torre M. Uniportal video-assisted thoracoscopic thymectomy and resection of a giant thymoma in a patient witness of Jehova[J]. J Thorac Dis, 2017,9(6):E556-E559. DOI: 10.21037/jtd.2017.05.06. doi: 10.21037/jtd.2017.05.06 pmid: 28740696
[12]	Chen H, Xu G, Zheng W, et al. Video-assisted thoracoscopic extended thymectomy using the subxiphoid approach[J]. J Vis Surg, 2016,2:157. DOI: 10.21037/jovs.2016.09.02. doi: 10.21037/jovs.2016.09.02 pmid: 29078543
[13]	沈明敬, 徐忠恒. 外科手术为主的胸腺瘤诊治进展[J]. 中华胸心血管外科杂志, 2015,31(5):317-320. DOI: 10.3760/cma.j.issn.1001-4497.2015.05.023.
[14]	Mineo TC, Ambrogi V. Surgical techniques for myasthenia gravis: video-assisted thoracic surgery[J]. Thorac Surg Clin, 2019,29(2):165-175. DOI: 10.1016/j.thorsurg.2018.12.005. doi: 10.1016/j.thorsurg.2018.12.005 pmid: 30927998
[15]	Karunanantham J, Fok M, Ali JM, et al. Subxiphoid single incision thoracoscopic surgery approach for thymectomy: a case report[J]. J Vis Surg, 2017,3:147. DOI: 10.21037/jovs.2017.10.03. doi: 10.21037/jovs.2017.10.03 pmid: 29302423
[16]	马骏, 白晓鸣, 韩丽娜, 等. 剑突下单孔胸腔镜手术26例报道[J]. 中国微创外科杂志, 2016,16(2):131-133. DOI: 10.3969/j.issn.1009-6604.2016.02.009.
[17]	彭凯明, 康明强, 林济红, 等. 经剑突下胸腔镜手术治疗前纵隔肿瘤疗效分析[J]. 中华胸部外科电子杂志, 2018,5(1):16-21.
[18]	Marulli G, Maessen J, Melfi F, et a1. Multi-institutional European experience of robotic thymectomy for thymoma[J]. Ann Cardiothorac Surg, 2016,5(1):18-25. DOI: 10.3978/j.issn.2225-319X.2015.08.13. doi: 10.3978/j.issn.2225-319X.2015.08.13 pmid: 26904427
[19]	O'Sullivan KE, Kreaden US, Hebert AE, et a1. A systematic review of robotic versus open and video assisted thoracoscopic surgery (VATS) approaches for thymectomy[J]. Ann Cardiothorac Surg, 2019,8(2):174-193. DOI: 10.21037/acs.2019.02.04. doi: 10.21037/acs.2019.02.04 pmid: 31032201
[20]	Nakadate R, Arata J, Hashizume M. Next-generation robotic surgery-from the aspect of surgical robots developed by industry[J]. Minim Invasive Ther Allied Technol, 2015,24(1):2-7. DOI: 10.3109/13645706.2014.1003140. doi: 10.3109/13645706.2014.1003140 pmid: 25627433
[21]	马永富, 杨博, 赵明, 等. 机器人辅助全胸腺切除术初步报道[J]. 中华腔镜外科杂志(电子版), 2017,10(2):74-76. DOI: 10.3877/cma.j.issn.1674-6899.2017.02.003.
[22]	Buentzel J, Straube C, Heinz J, et al. Thymectomy via open surgery or robotic video assisted thoracic surgery: can a recommendation already be made?[J]. Medicine (Baltimore), 2017,96(24):e7161. DOI: 10.1097/MD.0000000000007161. doi: 10.1097/MD.0000000000007161
[23]	Suda T. Robotic subxiphoid thymectomy[J]. J Vis Surg, 2016,2:118. DOI: 10.21037/jovs.2016.07.02. doi: 10.21037/jovs.2016.07.02 pmid: 29399504
[24]	张含露, 刘伦旭, 陈龙奇, 等. 机器人辅助经剑突下胸腺(扩大)切除手术的临床应用[J]. 中国胸心血管外科临床杂志, 2017,24(10):743-747. DOI: 10.7507/1007-4848.201708061.
[25]	Suda T, Kaneda S, Hachimaru A, et al. Thymectomy via a subxiphoid approach: single-port and robot-assisted[J]. J Thorac Dis, 2016,8(Suppl 3):S265-S271. DOI: 10.3978/j.issn.2072-1439.2016.02.34. doi: 10.3978/j.issn.2072-1439.2016.02.34 pmid: 27014473
[26]	Suda T, Tochii D, Tochii S, et al. Trans-subxiphoid robotic thymectomy[J]. Interact Cardiovasc Thorac Surg, 2015,20(5):669-671. DOI: 10.1093/icvts/ivv001. doi: 10.1093/icvts/ivv001 pmid: 25697983
[27]	关树斌, 谷志涛, 茅腾, 等. 胸腺肿瘤淋巴结转移的研究进展[J]. 临床外科杂志, 2019,27(7):622-625. DOI: 10.3969/j.issn.1005-6483.2019.07.028.
[28]	Weksler B, Pennathur A, Sullivan JL, et al. Resection of thymoma should include nodal sampling[J]. J Thorac Cardiovasc Surg, 2015,149(3):737-742. DOI: 10.1016/j.jtcvs.2014.11.054. doi: 10.1016/j.jtcvs.2014.11.054 pmid: 25595379
[29]	Zieliński M. Definitions and standard indications of minimally-invasive techniques in thymic surgery[J]. J Vis Surg, 2017,3:99. DOI: 10.21037/jovs.2017.06.04. pmid: 29078661
[30]	Banna GL, Sheel A, Sheel V, et al. Treatment and prognostic factors of patients with thymic epithelial tumors at first recurrence or progression[J]. Future Oncol, 2017,13(27):2429-2439. DOI: 10.2217/fon-2017-0236. doi: 10.2217/fon-2017-0236 pmid: 29121777

胸腺上皮性肿瘤手术治疗研究进展

Research progress in surgical treatment of thymic epithelial tumors

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