Abstract: SOX7 belongs to the SOX gene family. And it has been shown to regulate multiple biological processes. Studies have found that SOX7 gene is likely to be a tumor suppressor gene. In many tumors, SOX7 downregulation that inhibits proliferation, migration and invation of tumor via regulating the Wntβcatenin signaling pathway mediated the transcription process, which plays a significant role in tumorigenesis.

Key words: Transcription factors, Genes, tumor suppressor, SOX7