Roles of carcinoembryonic antigen-related adhesion molecules in lung cancer

Journal of International Oncology ›› 2013, Vol. 40 ›› Issue (10): 765-768.

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Roles of carcinoembryonic antigen-related adhesion molecules in lung cancer

WANG Xiu-Xiu, ZHANG Xiao-Jie, ZHANG Hua

Sixth Department of Internal Medicine, Affiliated Tumor Hospital of Harbin Medical University, Harbin 150081, China

Online:2013-10-08 Published:2013-09-23
Contact: ZHANG Hua, E-mail: zhanghua07＠126.com E-mail:zhanghua07＠126.com

Abstract

Abstract: Carcinoembryonic antigen-related adhesion molecules (CEACAMs) belong to the immunoglobulin superfamily. Related studies show that CEACAMs play an critical role in the occurrence and development , and are closely related to the prognosis of lung cancer. Recently, it has made some progresses in the studies by using monoclonal antibodies, single domain antibodies, RNA interference, gene knockout and other technical means targeting different epitopes of CEACAMs in lung cancer, suggesting CEACAMs may become new diagnostic biomarkers and therapeutic targets of lung cancer.

Key words: Carcinoembryonic antigen-related adhesion molecules, Lung neoplasms, Prognosis

WANG Xiu-Xiu, ZHANG Xiao-Jie, ZHANG Hua. Roles of carcinoembryonic antigen-related adhesion molecules in lung cancer[J]. Journal of International Oncology, 2013, 40(10): 765-768.

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Roles of carcinoembryonic antigen-related adhesion molecules in lung cancer

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