Journal of International Oncology ›› 2021, Vol. 48 ›› Issue (6): 370-373.doi: 10.3760/cma.j.cn371439-20201119-00071

• Reviews • Previous Articles     Next Articles

Research on the correlation between driver genes of lung adenocarcinoma and venous thromboembolism

Li Tiantian1, Shi Licheng2, Kong Hui1, Qi Xu1()   

  1. 1Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    2Department of Respiratory Medicine, Geriatric Hospital of Nanjing Medical University, Nanjing 210029, China
  • Received:2020-11-19 Revised:2020-12-28 Online:2021-06-08 Published:2021-06-24
  • Contact: Qi Xu E-mail:qixuly@163.com
  • Supported by:
    Scientific Research Project of Health Commission of Jiangsu Province of China(LGY2018054);Scientific Research Project of Health Commission of Jiangsu Province of China(H2019029);Beijing Medical and Health Foundation(F2135E)

Abstract:

Venous thromboembolism (VTE) is one of the common complications of lung adenocarci-noma. The state of the driver genes of lung adenocarcinoma is related to the risk of VTE. The common driver genes include epidermal growth factor receptor, anaplastic lymphoma kinase, c-ros oncogene 1 receptor kinase and Kirsten rat sarcoma viral oncogene, etc.. Based on the study of the correlation between lung adenocarci-noma driver genes and VTE, it is of great significance for the early clinical prevention of VTE in patients with lung adenocarcinoma to screen out patients with high risk of VTE according to the state of the driver genes and finally evaluate the risk of VTE in patients with lung adenocarcinoma by combining conventional risk factors with the driver genes.

Key words: Lung neoplasms, Adenocarcinoma, Venous thromboembolism, Driver gene